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Essential Thrombocythemia

by Pardanani, Animesh , Tefferi, Ayalew

in Age / Aspirin / Aspirin - therapeutic use / Biopsy / Blood platelets / Bone marrow / Calreticulin - genetics / Cancer / Cardiovascular diseases / Diagnosis, Differential / Family medical history / Female / Humans / Hydroxyurea / Hypertension / Janus kinase 2 / Laboratories / Medical prognosis / Megakaryocytes - pathology / Middle Aged / Mutation / Patients / Platelet Aggregation Inhibitors - therapeutic use / Platelet Count / Practice Guidelines as Topic / Risk factors / Thrombocythemia, Essential - diagnosis / Thrombocythemia, Essential - drug therapy / Thrombocythemia, Essential - pathology / Thromboembolism / Thrombosis / Tumors / Watchful Waiting / α-Interferon

2019

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Essential Thrombocythemia

by Pardanani, Animesh , Tefferi, Ayalew

2019

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Essential Thrombocythemia

by Pardanani, Animesh , Tefferi, Ayalew

2019

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Journal Article

Essential Thrombocythemia

Pardanani, Animesh,

Tefferi, Ayalew

2019

Overview

Essential thrombocythemia is associated with increased risks of bleeding and thrombosis. Estimation of the risk of thrombosis is based on history of thrombosis, presence of the JAK2 V617F mutation, age, and cardiovascular risk. Treatment commonly involves low-dose aspirin; therapy is used in patients with high thrombotic risk.

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Publisher

Massachusetts Medical Society

Subject

Age

/ Aspirin

/ Aspirin - therapeutic use

/ Biopsy

/ Blood platelets

/ Bone marrow

/ Calreticulin - genetics