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Isolation of Clostridium difficile at a University Hospital: A Two-Year Study
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Isolation of Clostridium difficile at a University Hospital: A Two-Year Study
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Journal Article
Isolation of Clostridium difficile at a University Hospital: A Two-Year Study
1995
Overview
Clostridium difficile is a leading cause of outbreaks of nosocomial diarrheal disease among hospitalized patients. The primary objective of this study was to observe all patients in the University of Kentucky Hospital who had C. difficile or its toxin isolated from stool specimens during the-2-year period April 1990 to April 1992. These patients were evaluated for clinical signs and symptoms of disease, demographic data, causative antibiotics, and treatment of disease associated with C. difficile. The secondary objective was to obtain and evaluate epidemiological data in a nonepidemic setting in a tertiary care center. The University of Kentucky Hospital is a 478-bed regional referral center and teaching hospital that serves central and eastern Kentucky. A retrospective surveillance of all cases of C. difficile disease was carded out by reviewing the results of assays performed by the clinical microbiology laboratory from April 1990 to April 1992. Clinical and patient data were ascertained by medical chart review, and data on demographics, medical history, symptoms, associated medical conditions, and treatments were recorded.
Publisher
The University of Chicago Press,University of Chicago Press
Subject
/ Adult
/ Aged
/ Bacterial diseases of the digestive system and abdomen
/ Biological and medical sciences
/ Child
/ Clostridium difficile - isolation & purification
/ Clostridium difficile - metabolism
/ Colitis
/ Cross Infection - epidemiology
/ Cross Infection - microbiology
/ Diarrhea
/ Enterocolitis, Pseudomembranous - epidemiology
/ Enterocolitis, Pseudomembranous - microbiology
/ Female
/ Humans
/ Infant
/ Male
/ Symptoms
