Asset Details
Do you wish to reserve the book?
Characterization of phenolic compounds using UPLC–HRMS and HPLC–DAD and anti-cholinesterase and anti-oxidant activities of Trifolium repens L. leaves
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Characterization of phenolic compounds using UPLC–HRMS and HPLC–DAD and anti-cholinesterase and anti-oxidant activities of Trifolium repens L. leaves
Do you wish to request the book?
Characterization of phenolic compounds using UPLC–HRMS and HPLC–DAD and anti-cholinesterase and anti-oxidant activities of Trifolium repens L. leaves
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Characterization of phenolic compounds using UPLC–HRMS and HPLC–DAD and anti-cholinesterase and anti-oxidant activities of Trifolium repens L. leaves
2020
Overview
This study was aimed to investigate the phenolic profile of methanolic extract of Trifolium repens L. leaves using LC–HRMS and LC–DAD and its anti--cholinesterase and anti-oxidant activities. The n-Hexane (Tr.Hex), chloroform (Tr.Chf), ethanol (Tr.Et), methanol (Tr.Cme), and aqueous (Tr.Aq) extracts were tested for anti-cholinesterases and anti-oxidant potentials. Twenty-nine phenolic compounds were quantified and identified. The highest amount present were of tyrosol (11.1 mg/g), quercetin-3-glucuronide (5.36 mg/g), formononetin-7-glucoside (5.03 mg/g), quercetin-3-O-glucoside (4.71 mg/g), 3,4-di-O-caffeoylquinic acid (4.69 mg/g), formononetin-7-glucoside-acetate (4.29 mg/g), quercetin-3-O-glucoside (4.26 mg/g), and formononetin (3.64 mg/g). Tr.Chf and Tr.Et were most active against AChE, BChE, and free radicals. Tr.Chf exhibited IC50 of 15 and 21 µg/mL against AChE and BChE, respectively. In the anti-oxidant study, Tr.Chf showed IC50 of 42 and 25 µg/mL against ABTS and DPPH radicals, respectively. The current results of anti-cholinesterase and anti-radical studies on T. repens further signify its potential application in neurodegenerative disorders.Graphic abstract
