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First trial of ‘base editing’ in humans lowers cholesterol — but raises safety concerns
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First trial of ‘base editing’ in humans lowers cholesterol — but raises safety concerns
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Journal Article
First trial of ‘base editing’ in humans lowers cholesterol — but raises safety concerns
2023
Overview
Super-precise gene-editing approach switches off a gene in the liver that regulates ‘bad’ cholesterol.
Super-precise gene-editing approach switches off a gene in the liver that regulates ‘bad’ cholesterol.
Credit: Steve Gschmeissner/Science Photo Library
Coloured SEM of cholesterol crystals (red) within a lipid droplet in a human liver.
