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Multiomics STEP up in correlative analysis of response to CAR T cells
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Journal Article
Multiomics STEP up in correlative analysis of response to CAR T cells
2023
Overview
Plasma cell-free DNA analysis has emerged as a powerful liquid biopsy assay to assess circulating tumour DNA in response to cancer treatments. A new study shows that cell-free DNA can also inform on expansion kinetics and tumour-infiltration patterns in patients receiving chimeric antigen receptor T cells and, together with circulating tumour DNA, provides vivid prognostic insights into intratumoural dynamics.
Publisher
Nature Publishing Group
Subject
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