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Therapeutic Strategies for Postherpetic Neuralgia: Mechanisms, Treatments, and Perspectives
by
Zeng, Anqi
, Song, Linjiang
, Liu, Chenxin
, Tang, Jiayu
, Zhang, Yunchao
in
Antidepressants
/ Deafness
/ Drug dosages
/ Drug efficacy
/ Headaches
/ Hypotheses
/ Internal Medicine
/ Medicine
/ Medicine & Public Health
/ Neuropathic Pain (A Abd-Elsayed
/ Older people
/ Pacemakers
/ Pain
/ Pain Medicine
/ Section Editor
/ Topical Collection on Neuropathic Pain
/ Traditional Chinese medicine
2023
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Therapeutic Strategies for Postherpetic Neuralgia: Mechanisms, Treatments, and Perspectives
by
Zeng, Anqi
, Song, Linjiang
, Liu, Chenxin
, Tang, Jiayu
, Zhang, Yunchao
in
Antidepressants
/ Deafness
/ Drug dosages
/ Drug efficacy
/ Headaches
/ Hypotheses
/ Internal Medicine
/ Medicine
/ Medicine & Public Health
/ Neuropathic Pain (A Abd-Elsayed
/ Older people
/ Pacemakers
/ Pain
/ Pain Medicine
/ Section Editor
/ Topical Collection on Neuropathic Pain
/ Traditional Chinese medicine
2023
Oops! Something went wrong.
While trying to remove the title from your shelf something went wrong :( Kindly try again later!
Do you wish to request the book?
Therapeutic Strategies for Postherpetic Neuralgia: Mechanisms, Treatments, and Perspectives
by
Zeng, Anqi
, Song, Linjiang
, Liu, Chenxin
, Tang, Jiayu
, Zhang, Yunchao
in
Antidepressants
/ Deafness
/ Drug dosages
/ Drug efficacy
/ Headaches
/ Hypotheses
/ Internal Medicine
/ Medicine
/ Medicine & Public Health
/ Neuropathic Pain (A Abd-Elsayed
/ Older people
/ Pacemakers
/ Pain
/ Pain Medicine
/ Section Editor
/ Topical Collection on Neuropathic Pain
/ Traditional Chinese medicine
2023
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Therapeutic Strategies for Postherpetic Neuralgia: Mechanisms, Treatments, and Perspectives
Journal Article
Therapeutic Strategies for Postherpetic Neuralgia: Mechanisms, Treatments, and Perspectives
2023
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Overview
Purpose of Review
Postherpetic neuralgia is an annoying pain that mainly affects older people. In order to give patients more options, this review summarizes the pharmacological and interventional treatments for postherpetic neuralgia and updates the research on the efficacy, thereby providing doctors with more treatment options. The adverse effects and effective doses of its various treatments are also presented so that the therapy can be prescribed according to their concrete physical conditions. In a word, this review is dedicated to providing a comprehensive overview of the treatment options for postherpetic neuralgia and offering patients more choices.
Recent Findings
Combinational therapy is more excellent than monotherapy. The local anesthesia and gabapentin comprised outstanding compatibility. In addition, two therapeutic tools for PHN patients, especially for the intractable ones, electroacupuncture (EA), and osteopathic manipulative treatment (OMT), show their efficacy and become potential options to alleviate pain.
Summary
In terms of treatment, guidelines recommend patients use tricyclic antidepressants (TCAs), gabapentin, pregabalin, and 5% lidocaine patches as the first-line medications, and gabapentin is investigated most, especially the gabapentin enacarbil (GEn). And drug efficacy can be limited by adverse effects and tolerated doses. Interventional treatments, with their invasiveness and operational difficulty, are usually considered for intractable patients. Combinational therapies may be used when a single therapy cannot achieve the desired effect. Therapies such as OMT and EA have also been proposed to palliate pain in some cases, and future directions of treatment may be investigated in Chinese medicine and acupuncture.
Publisher
Springer US,Springer Nature B.V
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