Asset Details
Do you wish to reserve the book?
The association between BMI trajectories and bronchopulmonary dysplasia among very preterm infants
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
The association between BMI trajectories and bronchopulmonary dysplasia among very preterm infants
Do you wish to request the book?
The association between BMI trajectories and bronchopulmonary dysplasia among very preterm infants
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
The association between BMI trajectories and bronchopulmonary dysplasia among very preterm infants
2023
Overview
Objective
To investigate the association between change in body mass index (BMI) from birth to 36 weeks gestation (ΔBMI) and bronchopulmonary dysplasia (BPD) among infants born <30 weeks gestation.
Methods
This was a multicenter retrospective cohort study (2015–2018) of infants born <30 weeks gestation and alive at ≥34 weeks corrected. Main exposure was a change in BMI
z
score from birth to 36 weeks corrected age grouped into quartiles of change. Association between ΔBMI
z
scores and BPD was assessed using generalized linear mixed models.
Results
Among 772 included infants, 51% developed BPD. From birth to 36 weeks CGA, the weight
z
score of infants with BPD decreased less than for BPD-free infants, despite a greater decrease in length
z
score and similar caloric intake resulting in increases in BMI
z
score (median [IQR], 0.16 [–0.64; 1.03] vs –0.29 [–1.03; 0.49];
P
< 0.01). In the adjusted analysis, higher ΔBMI
z
score quartiles were associated with higher odds of BPD (Q3 vs Q2, AOR [95% CI], 2.02 [1.23; 3.31] and Q4 vs Q2, AOR [95% CI], 2.00 [1.20; 3.34]).
Conclusion
Among preterm infants, an increase in BMI
z
score from birth to 36 weeks corrected is associated with higher odds of BPD.
Impact
Preterm infants with evolving lung disease often experience disproportionate growth in the neonatal period. In this multicenter cohort study, increases in BMI
z
score from birth to 36 weeks CGA were associated with higher odds of BPD.
Despite similar caloric intake, infants with BPD had a higher weight- but lower length-for-age, resulting in higher BMI
z
score compared to BPD-free infants.
This suggests that infants with evolving BPD may require different growth and nutritional targets compared to BPD-free infants.
Publisher
Nature Publishing Group US,Nature Publishing Group
Subject
