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Lenient versus Strict Rate Control in Patients with Atrial Fibrillation
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Lenient versus Strict Rate Control in Patients with Atrial Fibrillation
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Journal Article
Lenient versus Strict Rate Control in Patients with Atrial Fibrillation
2010
Overview
This clinical trial of outcomes in patients with atrial fibrillation showed that lenient rate control (resting heart rate, <110 beats per minute) was not inferior to strict rate control (resting heart rate, <80 beats per minute). On the basis of the results, strict rate control may be abandoned as a therapeutic strategy in many patients with permanent atrial fibrillation.
In patients with atrial fibrillation, lenient rate control (resting heart rate, <110 beats per minute) was not inferior to strict rate control (resting heart rate, <80 beats per minute).
Atrial fibrillation is not a benign condition.
1
It may cause symptoms and is associated with stroke and heart failure. Previous studies have established that the rates of complications and death were similar in patients with atrial fibrillation receiving rate-control therapy and in those receiving rhythm-control therapy.
2
,
3
Therefore, rate control has become front-line therapy in the management of atrial fibrillation. The optimal level of heart-rate control, however, is unknown, as is whether strict rate control is associated with an improved prognosis as compared with a more lenient approach.
2
–
6
Guidelines, though empirical and not evidence-based, recommend the use of strict . . .
Publisher
Massachusetts Medical Society
Subject
Adrenergic beta-Antagonists - therapeutic use
/ Aged
/ Anti-Arrhythmia Agents - therapeutic use
/ Atrial Fibrillation - complications
/ Atrial Fibrillation - drug therapy
/ Atrial Fibrillation - mortality
/ Atrial Fibrillation - physiopathology
/ Biological and medical sciences
/ Calcium Channel Blockers - therapeutic use
/ Female
/ Heart
/ Humans
/ Male
