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Cancer Risk among Children Born after Assisted Conception
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Journal Article
Cancer Risk among Children Born after Assisted Conception
2013
Overview
In a large study using registry data from Britain, overall cancer incidence was not increased among children born after assisted conception. Assisted conception was associated with an increased risk of hepatoblastoma and rhabdomyosarcoma, but the absolute risks were small.
Since the introduction of in vitro fertilization (IVF) in 1978, the number and proportion of children born after assisted conception have increased annually, and currently there are more than 5 million such persons worldwide.
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Well-recognized perinatal complications in this population include low birth weight, prematurity, and congenital malformations.
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–
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However, there remains a dearth of population-based studies investigating important but rare health outcomes.
The possibility of an increased risk of cancer in this population has been suggested previously.
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–
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This concern is supported by the discovery of altered epigenetic patterns in human embryos,
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,
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cord blood,
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and placentas
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,
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after . . .
Publisher
Massachusetts Medical Society
Subject
/ Age
/ Biological and medical sciences
/ Cancer
/ Child
/ Children
/ Embryos
/ Female
/ Hepatoblastoma - epidemiology
/ Humans
/ Infant
/ Liver Neoplasms - epidemiology
/ Male
/ Multiple tumors. Solid tumors. Tumors in childhood (general aspects)
/ Reproductive Techniques, Assisted - adverse effects
/ Retina
/ Rhabdomyosarcoma - epidemiology
/ Risk
/ Software
/ Sperm
/ Tumors
