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Routine Amoxicillin for Uncomplicated Severe Acute Malnutrition in Children
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Routine Amoxicillin for Uncomplicated Severe Acute Malnutrition in Children
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Journal Article
Routine Amoxicillin for Uncomplicated Severe Acute Malnutrition in Children
2016
Overview
The role of routine antibiotic use in the treatment of severe acute malnutrition is unclear. In this randomized, placebo-controlled trial in Niger, amoxicillin did not significantly improve nutritional recovery in children with severe acute malnutrition.
Severe acute malnutrition affects approximately 19 million children under 5 years of age worldwide and contributes substantially to mortality and the disease burden among children.
1
To reduce the risk of death from severe acute malnutrition, specialized nutritional and medical intervention is required. Bacterial infection can complicate advanced cases of severe acute malnutrition,
2
–
9
and the risk of nosocomial infection in inpatient settings can be high. Therefore, in 1999, when all children with severe acute malnutrition were treated as inpatients, the World Health Organization (WHO) recommended routine use of broad-spectrum antibiotics for the management of severe acute malnutrition, irrespective of clinical . . .
Publisher
Massachusetts Medical Society
Subject
/ Amoxicillin - therapeutic use
/ Anti-Bacterial Agents - therapeutic use
/ Bacterial Infections - complications
/ Bacterial Infections - drug therapy
/ Bacterial Infections - epidemiology
/ Children
/ Female
/ Humans
/ Infant
/ Male
/ Severe Acute Malnutrition - complications
/ Severe Acute Malnutrition - drug therapy
