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Perioperative Durvalumab in Gastric and Gastroesophageal Junction Cancer
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Perioperative Durvalumab in Gastric and Gastroesophageal Junction Cancer
Perioperative Durvalumab in Gastric and Gastroesophageal Junction Cancer
Journal Article

Perioperative Durvalumab in Gastric and Gastroesophageal Junction Cancer

2025
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Overview
In resectable gastric and gastroesophageal junction cancer, adding durvalumab to perioperative chemotherapy improved event-free survival and pathological complete response, with no major increase in high-grade adverse events.
Publisher
Massachusetts Medical Society
Subject

5-Fluorouracil

/ Adenocarcinoma

/ Adenocarcinoma - drug therapy

/ Adenocarcinoma - mortality

/ Adenocarcinoma - pathology

/ Adenocarcinoma - surgery

/ Adjuvant therapy

/ Adjuvants

/ Adult

/ Aged

/ Aged, 80 and over

/ Antibodies, Monoclonal - administration & dosage

/ Antibodies, Monoclonal - adverse effects

/ Antineoplastic Agents, Immunological - administration & dosage

/ Antineoplastic Agents, Immunological - adverse effects

/ Antineoplastic Combined Chemotherapy Protocols - administration & dosage

/ Antineoplastic Combined Chemotherapy Protocols - adverse effects

/ Biopsy

/ Cancer therapies

/ Chemotherapy

/ Chemotherapy, Adjuvant - adverse effects

/ Chemotherapy, Adjuvant - methods

/ Clinical medicine

/ Consent

/ Docetaxel - administration & dosage

/ Docetaxel - adverse effects

/ Double-Blind Method

/ Esophageal Neoplasms - drug therapy

/ Esophageal Neoplasms - mortality

/ Esophageal Neoplasms - pathology

/ Esophageal Neoplasms - surgery

/ Esophagogastric Junction - pathology

/ Esophagogastric Junction - surgery

/ Female

/ Fluorouracil - administration & dosage

/ Fluorouracil - adverse effects

/ Gastroenterology

/ Gastrointestinal Tract Cancer

/ Hematology

/ Humans

/ Immunotherapy

/ Kaplan-Meier Estimate

/ Leucovorin - administration & dosage

/ Leucovorin - adverse effects

/ Male

/ Metastasis

/ Middle Aged

/ Neoadjuvant Therapy - adverse effects

/ Neoadjuvant Therapy - methods

/ Oncology

/ Oxaliplatin

/ Oxaliplatin - administration & dosage

/ Oxaliplatin - adverse effects

/ Perioperative Care - adverse effects

/ Perioperative Care - methods

/ Placebos

/ Statistical analysis

/ Stomach Neoplasms - drug therapy

/ Stomach Neoplasms - mortality

/ Stomach Neoplasms - pathology

/ Stomach Neoplasms - surgery

/ Surgery

/ Survival

/ Survival analysis

/ Treatment Outcome

/ Treatments in Oncology

/ Tumors