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Twin-to-Twin Transfusion Syndrome: From Observational Evidence to Randomized Controlled Trials
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Journal Article
Twin-to-Twin Transfusion Syndrome: From Observational Evidence to Randomized Controlled Trials
2016
Overview
Fetoscopic surgery is widely accepted as the preferred first-line treatment for twin–twin transfusion syndrome (TTTS). Nonetheless, the broad diffusion of this technique relies on a single multicentric-randomized trial. We hereby question this trial in a post-hoc Bayesian analysis, submitting its results to several scenarios comprising the alternative published non-randomized literature and pessimistic opinions regarding this surgery. Furthermore, we also discuss further refinements in indications, questioning potential alternatives in early stages of the disease.
Publisher
Cambridge University Press
