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Factors and Outcomes Associated With Early and Delayed Aneurysm Treatment in Subarachnoid Hemorrhage Patients in the United States
by
Suri, M. Fareed K.
, Tummala, Ramachandra P.
, Chaudhry, Saqib A.
, Qureshi, Adnan I.
, Siddiq, Farhan
in
Aneurysm, Ruptured - complications
/ Aneurysm, Ruptured - mortality
/ Aneurysm, Ruptured - surgery
/ Aneurysms
/ Biological and medical sciences
/ Disability Evaluation
/ Early Medical Intervention
/ Embolization
/ Embolization, Therapeutic
/ Female
/ Hospital Mortality
/ Humans
/ Intracranial Aneurysm - complications
/ Intracranial Aneurysm - mortality
/ Intracranial Aneurysm - surgery
/ Male
/ Medical sciences
/ Neurosurgery
/ Stroke
/ Subarachnoid Hemorrhage - etiology
/ Subarachnoid Hemorrhage - mortality
/ Subarachnoid Hemorrhage - surgery
/ Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
/ Surgical Instruments
/ Time Factors
/ Treatment Outcome
/ United States - epidemiology
2012
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Factors and Outcomes Associated With Early and Delayed Aneurysm Treatment in Subarachnoid Hemorrhage Patients in the United States
by
Suri, M. Fareed K.
, Tummala, Ramachandra P.
, Chaudhry, Saqib A.
, Qureshi, Adnan I.
, Siddiq, Farhan
in
Aneurysm, Ruptured - complications
/ Aneurysm, Ruptured - mortality
/ Aneurysm, Ruptured - surgery
/ Aneurysms
/ Biological and medical sciences
/ Disability Evaluation
/ Early Medical Intervention
/ Embolization
/ Embolization, Therapeutic
/ Female
/ Hospital Mortality
/ Humans
/ Intracranial Aneurysm - complications
/ Intracranial Aneurysm - mortality
/ Intracranial Aneurysm - surgery
/ Male
/ Medical sciences
/ Neurosurgery
/ Stroke
/ Subarachnoid Hemorrhage - etiology
/ Subarachnoid Hemorrhage - mortality
/ Subarachnoid Hemorrhage - surgery
/ Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
/ Surgical Instruments
/ Time Factors
/ Treatment Outcome
/ United States - epidemiology
2012
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Factors and Outcomes Associated With Early and Delayed Aneurysm Treatment in Subarachnoid Hemorrhage Patients in the United States
by
Suri, M. Fareed K.
, Tummala, Ramachandra P.
, Chaudhry, Saqib A.
, Qureshi, Adnan I.
, Siddiq, Farhan
in
Aneurysm, Ruptured - complications
/ Aneurysm, Ruptured - mortality
/ Aneurysm, Ruptured - surgery
/ Aneurysms
/ Biological and medical sciences
/ Disability Evaluation
/ Early Medical Intervention
/ Embolization
/ Embolization, Therapeutic
/ Female
/ Hospital Mortality
/ Humans
/ Intracranial Aneurysm - complications
/ Intracranial Aneurysm - mortality
/ Intracranial Aneurysm - surgery
/ Male
/ Medical sciences
/ Neurosurgery
/ Stroke
/ Subarachnoid Hemorrhage - etiology
/ Subarachnoid Hemorrhage - mortality
/ Subarachnoid Hemorrhage - surgery
/ Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
/ Surgical Instruments
/ Time Factors
/ Treatment Outcome
/ United States - epidemiology
2012
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Factors and Outcomes Associated With Early and Delayed Aneurysm Treatment in Subarachnoid Hemorrhage Patients in the United States
Journal Article
Factors and Outcomes Associated With Early and Delayed Aneurysm Treatment in Subarachnoid Hemorrhage Patients in the United States
2012
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Overview
Abstract
BACKGROUND:
Recent studies from selected centers have shown that early surgical treatment of aneurysms in subarachnoid hemorrhage (SAH) patients can improve outcomes. These results have not been validated in clinical practice at large.
OBJECTIVE:
To identify factors and outcomes associated with timing of ruptured intracranial aneurysm obliteration treatment in patients with SAH after hospitalization in the United States.
METHODS:
We analyzed the data from the Nationwide Inpatient Sample (2005–2008) for all patients presenting with primary diagnosis of SAH, receiving aneurysm treatment (endovascular coil embolization or surgical clip placement). Early treatment was defined as aneurysm treatment performed within 48 hours and delayed treatment if treatment was performed after 48 hours of admission.
RESULTS:
Of 32 048 patients with SAH who underwent aneurysm treatment, 24 085 (75.2%) underwent early treatment and 7963 (24.8%) underwent delayed treatment. Female sex (P = .002), endovascular embolization (P < .001), and weekday admission (P < .001) were independent predictors of early treatment. In the early treatment group, patients were more likely discharged with none to minimal disability (odds ratio [OR] 1.30, 95% confidence interval [CI] 1.14-1.47) and less likely to be discharged with moderate to severe disability (OR 0.77, 95%CI 0.67-0.87) compared with those in the delayed treatment group. The in-hospital mortality was higher in the early treatment group compared with the delayed treatment group (OR 1.36 95%CI 1.12-1.66).
CONCLUSION:
Patients with SAH who undergo aneurysm treatment within 48 hours of hospital admission are more likely to be discharged with none to minimal disability. Early treatment is more likely to occur in those undergoing endovascular treatment and in patients admitted on weekdays.
Publisher
Oxford University Press,Lippincott Williams & Wilkins,Wolters Kluwer Health, Inc
Subject
Aneurysm, Ruptured - complications
/ Aneurysm, Ruptured - mortality
/ Aneurysm, Ruptured - surgery
/ Biological and medical sciences
/ Female
/ Humans
/ Intracranial Aneurysm - complications
/ Intracranial Aneurysm - mortality
/ Intracranial Aneurysm - surgery
/ Male
/ Stroke
/ Subarachnoid Hemorrhage - etiology
/ Subarachnoid Hemorrhage - mortality
/ Subarachnoid Hemorrhage - surgery
/ Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
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