Journal Article

Childhood Intussusception after Introduction of Indigenous Rotavirus Vaccine: Hospital-Based Surveillance Study from Odisha, India

Reddy N, Samarasimha, Das, Rashmi Ranjan, Satpathy, Saroj Kumar, Prusty, J. Bikrant, Mohanty, Subrat Kumar, Das, Mirabai, Ray, Rajib Kumar, Chaudhury, Jasashree, Nayak, Manas Kumar, Pradhan, Subal Kumar, Padhi, Pooja Sagar, Mohakud, Nirmal Kumar, Dash, Mrutunjay

2021

Overview

ObjectiveTo study the epidemiology of intussusception in children < 2 y of age, postintroduction of Rotavac® (an indigenous oral rotavirus vaccine).MethodsA multicenter hospital-based surveillance was conducted in Odisha from February 2016 to June 2019. The cases were diagnosed according to Brighton level-1 criteria. Data were collected regarding the time of onset, signs and symptoms, radiological diagnosis, management, complications, and outcome (discharged/died).ResultsOne hundred and twenty children < 2 y of age were enrolled. The median age was 7 mo (M:F ratio = 2:1). The most common clinical feature was abdominal distention and blood in stool. The most common method for treatment was hydrostatic/pneumatic reduction. Median time (days) between symptom onset and admission was 2. Median (IQR) duration (days) of hospitalization was 5. Most common location of intussusceptions was ileo-colic.ConclusionsHydrostatic/pneumatic reduction was possible in the majority presenting ≤ 48 h of symptom onset, and those presenting > 48 h mostly required surgical reduction. Intestinal resection was required in some cases presenting on day 5 of symptom onset. Majority of cases were managed by surgical reduction in Government facility.

• Publisher: Springer Nature B.V
• Subject: Abdomen / Age / Autopsies / Childhood / Diarrhea / Hospitalization / Immunization / Intestinal obstruction / Mortality / Pediatrics / Peritonitis / Rotavirus / Surgery / Surveillance / Vaccines / Viruses / Vomiting