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Immediate versus Postponed Intervention for Infected Necrotizing Pancreatitis

by van Lienden, Krijn P , Voermans, Rogier P , Poen, Alexander C , Straathof, Jan Willem A , Cappendijk, Vincent C , van Dijk, Sven M , van Eijck, Casper H.J , Römkens, Tessa E.H , Boxhoorn, Lotte , van Duijvendijk, Peter , Hallensleben, Nora D.L , Mieog, J. Sven D , Molenaar, I. Quintus , Poley, Jan-Werner , van Santvoort, Hjalmar C , Verdonk, Robert C , Jansen, Jeroen M , Bouwense, Stefan A.W , Manusama, Eric R , Dijkgraaf, Marcel G.W , Bruno, Marco J , Haveman, Jan Willem , Stommel, Martijn W.J , Jacobs, Maarten A.J.M , Schwartz, Matthijs P , Seerden, Tom C , Quispel, Rutger , Boermeester, Marja A , Nieuwenhuijs, Vincent B , Dejong, Cornelis H.C , van de Vrie, Wim , Besselink, Marc G , Witteman, Ben J , Timmerhuis, Hester C , van de Poll, Marcel , van Goor, Harry , Francken, Michiel F.G , Hadithi, Muhammed , Bollen, Thomas L , Kop, Marnix P.M , Venneman, Niels G , van Grinsven, Janneke , Fockens, Paul

in Abdomen / Aged / Anti-Bacterial Agents - therapeutic use / Antibiotics / Catheters / Classification / Clinical Practice / Combined Modality Therapy / Confidence intervals / Drainage / Endoscopy / Female / Fistula / Gastroenterology / Gastroenterology General / Hospital costs / Hospitalist / Humans / Infections / Infectious Disease / Infectious Disease General / Intensive care / Intervention / Length of Stay / Male / Middle Aged / Necrosis / Pancreas - pathology / Pancreas - surgery / Pancreatitis / Pancreatitis, Acute Necrotizing - drug therapy / Pancreatitis, Acute Necrotizing - pathology / Pancreatitis, Acute Necrotizing - surgery / Pancreatitis, Acute Necrotizing - therapy / Patient safety / Primary Care / Surgery / Surgery General / Surgical drains / Time-to-Treatment / Wound drainage

2021

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2021

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2021

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Journal Article

Immediate versus Postponed Intervention for Infected Necrotizing Pancreatitis

van Lienden, Krijn P,

Voermans, Rogier P,

Poen, Alexander C,

Straathof, Jan Willem A,

Cappendijk, Vincent C,

van Dijk, Sven M,

van Eijck, Casper H.J,

Römkens, Tessa E.H,

Boxhoorn, Lotte,

van Duijvendijk, Peter,

Hallensleben, Nora D.L,

Mieog, J. Sven D,

Molenaar, I. Quintus,

Poley, Jan-Werner,

van Santvoort, Hjalmar C,

Verdonk, Robert C,

Jansen, Jeroen M,

Bouwense, Stefan A.W,

Manusama, Eric R,

Dijkgraaf, Marcel G.W,

Bruno, Marco J,

Haveman, Jan Willem,

Stommel, Martijn W.J,

Jacobs, Maarten A.J.M,

Schwartz, Matthijs P,

Seerden, Tom C,

Quispel, Rutger,

Boermeester, Marja A,

Nieuwenhuijs, Vincent B,

Dejong, Cornelis H.C,

van de Vrie, Wim,

Besselink, Marc G,

Witteman, Ben J,

Timmerhuis, Hester C,

van de Poll, Marcel,

van Goor, Harry,

Francken, Michiel F.G,

Hadithi, Muhammed,

Bollen, Thomas L,

Kop, Marnix P.M,

Venneman, Niels G,

van Grinsven, Janneke,

Fockens, Paul

2021

Overview

A multicenter, randomized trial of patients with infected necrotizing pancreatitis evaluated immediate drainage within 24 hours after infected necrosis was diagnosed as compared with postponed drainage. Immediate drainage was not superior to postponed drainage in reducing complications. Patients assigned to immediate drainage underwent a greater number of invasive procedures.

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Publisher

Massachusetts Medical Society

Subject

Abdomen

/ Aged

/ Anti-Bacterial Agents - therapeutic use