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Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes
by
Tack, Cees J
, Warren, Mark L
, Jeppesen, Ole K
, Mosenzon, Ofri
, Husain, Mansoor
, Donsmark, Morten
, Dungan, Kathleen
, Eliaschewitz, Freddy G
, Thomsen, Mette
, Bain, Stephen C
, Pedersen, Sue D
, Birkenfeld, Andreas L
, Franco, Denise R
, Vilsbøll, Tina
, Lingvay, Ildiko
in
Administration, Oral
/ Aged
/ Angina pectoris
/ Antidiabetics
/ Cardiovascular disease
/ Cardiovascular diseases
/ Cardiovascular Diseases - chemically induced
/ Cerebral infarction
/ Death
/ Diabetes
/ Diabetes mellitus
/ Diabetes mellitus (non-insulin dependent)
/ Diabetes Mellitus, Type 2 - complications
/ Diabetes Mellitus, Type 2 - drug therapy
/ Diabetic retinopathy
/ Double-Blind Method
/ Female
/ GLP-1 receptor agonists
/ Glucagon
/ Glucagon-like peptide 1
/ Glucagon-Like Peptide-1 Receptor - agonists
/ Glucagon-Like Peptides - administration & dosage
/ Glucagon-Like Peptides - adverse effects
/ Glucose
/ Glycated Hemoglobin A - analysis
/ Heart attacks
/ Heart failure
/ Hospitalization
/ Humans
/ Hypoglycemic Agents - administration & dosage
/ Hypoglycemic Agents - adverse effects
/ Kidney diseases
/ Laboratories
/ Male
/ Middle Aged
/ Myocardial infarction
/ Peptides
/ Risk
/ Risk factors
/ Stroke
/ Veins & arteries
2019
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Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes
by
Tack, Cees J
, Warren, Mark L
, Jeppesen, Ole K
, Mosenzon, Ofri
, Husain, Mansoor
, Donsmark, Morten
, Dungan, Kathleen
, Eliaschewitz, Freddy G
, Thomsen, Mette
, Bain, Stephen C
, Pedersen, Sue D
, Birkenfeld, Andreas L
, Franco, Denise R
, Vilsbøll, Tina
, Lingvay, Ildiko
in
Administration, Oral
/ Aged
/ Angina pectoris
/ Antidiabetics
/ Cardiovascular disease
/ Cardiovascular diseases
/ Cardiovascular Diseases - chemically induced
/ Cerebral infarction
/ Death
/ Diabetes
/ Diabetes mellitus
/ Diabetes mellitus (non-insulin dependent)
/ Diabetes Mellitus, Type 2 - complications
/ Diabetes Mellitus, Type 2 - drug therapy
/ Diabetic retinopathy
/ Double-Blind Method
/ Female
/ GLP-1 receptor agonists
/ Glucagon
/ Glucagon-like peptide 1
/ Glucagon-Like Peptide-1 Receptor - agonists
/ Glucagon-Like Peptides - administration & dosage
/ Glucagon-Like Peptides - adverse effects
/ Glucose
/ Glycated Hemoglobin A - analysis
/ Heart attacks
/ Heart failure
/ Hospitalization
/ Humans
/ Hypoglycemic Agents - administration & dosage
/ Hypoglycemic Agents - adverse effects
/ Kidney diseases
/ Laboratories
/ Male
/ Middle Aged
/ Myocardial infarction
/ Peptides
/ Risk
/ Risk factors
/ Stroke
/ Veins & arteries
2019
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Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes
by
Tack, Cees J
, Warren, Mark L
, Jeppesen, Ole K
, Mosenzon, Ofri
, Husain, Mansoor
, Donsmark, Morten
, Dungan, Kathleen
, Eliaschewitz, Freddy G
, Thomsen, Mette
, Bain, Stephen C
, Pedersen, Sue D
, Birkenfeld, Andreas L
, Franco, Denise R
, Vilsbøll, Tina
, Lingvay, Ildiko
in
Administration, Oral
/ Aged
/ Angina pectoris
/ Antidiabetics
/ Cardiovascular disease
/ Cardiovascular diseases
/ Cardiovascular Diseases - chemically induced
/ Cerebral infarction
/ Death
/ Diabetes
/ Diabetes mellitus
/ Diabetes mellitus (non-insulin dependent)
/ Diabetes Mellitus, Type 2 - complications
/ Diabetes Mellitus, Type 2 - drug therapy
/ Diabetic retinopathy
/ Double-Blind Method
/ Female
/ GLP-1 receptor agonists
/ Glucagon
/ Glucagon-like peptide 1
/ Glucagon-Like Peptide-1 Receptor - agonists
/ Glucagon-Like Peptides - administration & dosage
/ Glucagon-Like Peptides - adverse effects
/ Glucose
/ Glycated Hemoglobin A - analysis
/ Heart attacks
/ Heart failure
/ Hospitalization
/ Humans
/ Hypoglycemic Agents - administration & dosage
/ Hypoglycemic Agents - adverse effects
/ Kidney diseases
/ Laboratories
/ Male
/ Middle Aged
/ Myocardial infarction
/ Peptides
/ Risk
/ Risk factors
/ Stroke
/ Veins & arteries
2019
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Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes
Journal Article
Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes
2019
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Overview
Safety data exist for subcutaneous semaglutide, a glucagon-like peptide-1 receptor agonist, but not for the oral form. Here, oral semaglutide was assessed in a randomized, double-blind, placebo-controlled trial involving patients with type 2 diabetes at high cardiovascular risk; oral semaglutide was noninferior for cardiovascular safety.
Publisher
Massachusetts Medical Society
Subject
/ Aged
/ Cardiovascular Diseases - chemically induced
/ Death
/ Diabetes
/ Diabetes mellitus (non-insulin dependent)
/ Diabetes Mellitus, Type 2 - complications
/ Diabetes Mellitus, Type 2 - drug therapy
/ Female
/ Glucagon
/ Glucagon-Like Peptide-1 Receptor - agonists
/ Glucagon-Like Peptides - administration & dosage
/ Glucagon-Like Peptides - adverse effects
/ Glucose
/ Glycated Hemoglobin A - analysis
/ Humans
/ Hypoglycemic Agents - administration & dosage
/ Hypoglycemic Agents - adverse effects
/ Male
/ Peptides
/ Risk
/ Stroke
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