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Advancements in Photothermal Therapy Using Near-Infrared Light for Bone Tumors
by
Zhang, Xingdong
, Xie, Mengzhang
, Gong, Taojun
, Luo, Yi
, Tu, Chongqi
, Zhou, Yong
, Lu, Minxun
, Min, Li
, Zeng, Qin
, Li, Zhuangzhuang
, Wang, Yitian
in
Ablation
/ Angiogenesis
/ Animals
/ Apoptosis
/ B cells
/ Bone cancer
/ Bone Neoplasms - therapy
/ Bone Regeneration
/ Bone tumors
/ Cancer
/ Cancer therapies
/ Cell death
/ Chemotherapy
/ Combined Modality Therapy - methods
/ Energy
/ Health aspects
/ Heat
/ Humans
/ Hypoxia
/ Immunotherapy
/ Immunotherapy - methods
/ Infrared Rays - therapeutic use
/ Light
/ Light therapy
/ Medical technology
/ Metastasis
/ Mortality
/ Nanomaterials
/ Osteosarcoma - pathology
/ Osteosarcoma - therapy
/ Photochemotherapy
/ Photochemotherapy - methods
/ Photosensitizing Agents - therapeutic use
/ Photothermal Therapy - methods
/ Proteins
/ Quality of life
/ Radiation therapy
/ Sarcoma
/ Temperature
/ Tumors
2024
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Advancements in Photothermal Therapy Using Near-Infrared Light for Bone Tumors
by
Zhang, Xingdong
, Xie, Mengzhang
, Gong, Taojun
, Luo, Yi
, Tu, Chongqi
, Zhou, Yong
, Lu, Minxun
, Min, Li
, Zeng, Qin
, Li, Zhuangzhuang
, Wang, Yitian
in
Ablation
/ Angiogenesis
/ Animals
/ Apoptosis
/ B cells
/ Bone cancer
/ Bone Neoplasms - therapy
/ Bone Regeneration
/ Bone tumors
/ Cancer
/ Cancer therapies
/ Cell death
/ Chemotherapy
/ Combined Modality Therapy - methods
/ Energy
/ Health aspects
/ Heat
/ Humans
/ Hypoxia
/ Immunotherapy
/ Immunotherapy - methods
/ Infrared Rays - therapeutic use
/ Light
/ Light therapy
/ Medical technology
/ Metastasis
/ Mortality
/ Nanomaterials
/ Osteosarcoma - pathology
/ Osteosarcoma - therapy
/ Photochemotherapy
/ Photochemotherapy - methods
/ Photosensitizing Agents - therapeutic use
/ Photothermal Therapy - methods
/ Proteins
/ Quality of life
/ Radiation therapy
/ Sarcoma
/ Temperature
/ Tumors
2024
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Advancements in Photothermal Therapy Using Near-Infrared Light for Bone Tumors
by
Zhang, Xingdong
, Xie, Mengzhang
, Gong, Taojun
, Luo, Yi
, Tu, Chongqi
, Zhou, Yong
, Lu, Minxun
, Min, Li
, Zeng, Qin
, Li, Zhuangzhuang
, Wang, Yitian
in
Ablation
/ Angiogenesis
/ Animals
/ Apoptosis
/ B cells
/ Bone cancer
/ Bone Neoplasms - therapy
/ Bone Regeneration
/ Bone tumors
/ Cancer
/ Cancer therapies
/ Cell death
/ Chemotherapy
/ Combined Modality Therapy - methods
/ Energy
/ Health aspects
/ Heat
/ Humans
/ Hypoxia
/ Immunotherapy
/ Immunotherapy - methods
/ Infrared Rays - therapeutic use
/ Light
/ Light therapy
/ Medical technology
/ Metastasis
/ Mortality
/ Nanomaterials
/ Osteosarcoma - pathology
/ Osteosarcoma - therapy
/ Photochemotherapy
/ Photochemotherapy - methods
/ Photosensitizing Agents - therapeutic use
/ Photothermal Therapy - methods
/ Proteins
/ Quality of life
/ Radiation therapy
/ Sarcoma
/ Temperature
/ Tumors
2024
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Advancements in Photothermal Therapy Using Near-Infrared Light for Bone Tumors
Journal Article
Advancements in Photothermal Therapy Using Near-Infrared Light for Bone Tumors
2024
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Overview
Bone tumors, particularly osteosarcoma, are prevalent among children and adolescents. This ailment has emerged as the second most frequent cause of cancer-related mortality in adolescents. Conventional treatment methods comprise extensive surgical resection, radiotherapy, and chemotherapy. Consequently, the management of bone tumors and bone regeneration poses significant clinical challenges. Photothermal tumor therapy has attracted considerable attention owing to its minimal invasiveness and high selectivity. However, key challenges have limited its widespread clinical use. Enhancing the tumor specificity of photosensitizers through targeting or localized activation holds potential for better outcomes with fewer adverse effects. Combinations with chemotherapies or immunotherapies also present avenues for improvement. In this review, we provide an overview of the most recent strategies aimed at overcoming the limitations of photothermal therapy (PTT), along with current research directions in the context of bone tumors, including (1) target strategies, (2) photothermal therapy combined with multiple therapies (immunotherapies, chemotherapies, and chemodynamic therapies, magnetic, and photodynamic therapies), and (3) bifunctional scaffolds for photothermal therapy and bone regeneration. We delve into the pros and cons of these combination methods and explore current research focal points. Lastly, we address the challenges and prospects of photothermal combination therapy.
Publisher
MDPI AG
Subject
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