Journal Article

Prediction of Extrauterine Growth Retardation (EUGR) in VVLBW Infants

Rafail, Salisa T, Radmacher, Paula G, Adamkin, David H, Looney, Stephen W

2003

Overview

BACKGROUND: Long-term growth failure in very very low birth weight (VVLBW) infants is a common complication of extreme prematurity. Critical illnesses create challenges to adequate nutriture. PURPOSE: To identify predictors of extrauterine growth retardation (EUGR) in VVLBW infants and to evaluate their nutritional intake and subsequent growth. STUDY DESIGN: A 4-year retrospective chart review of 221 infants ≤1000 g birth weight and ≤29 weeks gestational age who were admitted within 24 hours of birth, were free of major congenital anomalies and survived at least 7 days. Daily intakes and anthropomorphic data were collected and analyzed. Significant events during hospitalization were documented. RESULTS: Mean energy and protein intakes during hospitalization did not reach recommendations of 120 kcal/kg/d and 3.0 g/kg/day. In utero growth rates could not be consistently reached or sustained. As expected, BW (as measured by BW percentile score) was highly predictive of EUGR ( p <0.001). When the independent effect of other predictors of EUGR was considered, only days of total parenteral nutrition ( p <0.001) and HC percentile at return to birth weight ( p <0.001) made a significant contribution to the prediction of EUGR, once the effect of BW was taken into account.

• Publisher: Nature Publishing Group US,Nature Publishing Group
• Subject: Birth weight / Birth weight, Low / Child, Preschool / Congenital anomalies / Congenital defects / Developmental Disabilities - epidemiology / Enteral nutrition / Female / Fetus / Follow-Up Studies / Gestational Age / Growth Disorders - diagnosis / Growth Disorders - epidemiology / Growth rate / Growth retardation / Hospitalization / Humans / Incidence / Infant / Infant Mortality / Infant Nutritional Physiological Phenomena / Infant, Newborn / Infant, Premature / Infant, Very Low Birth Weight / Infants / Intensive care / Intensive Care Units, Neonatal / Logistic Models / Low birth weight / Male / Medicine / Medicine & Public Health / Nutrition / Nutritional Requirements / original-article / Parenteral nutrition / Pediatric Surgery / Pediatrics / Physical growth / Predictive Value of Tests / Premature babies / Premature birth / Probability / Proteins / Regression analysis / Retrospective Studies / Risk Assessment / ROC Curve / Variables / Weight