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AR101 Oral Immunotherapy for Peanut Allergy

by Ohayon, Jason , Adelman, Daniel C , Yang, William H , Cheema, Amarjit , Sanders, Georgiana M , Zawadzki, Rezi , Sher, Lawrence , Spergel, Jonathan M , Beyer, Kirsten , Stillerman, Allan , Ciaccio, Christina E , Jeong, David K , Jones, Stacie M , Kim, Edwin H , Mansfield, Lyndon E , Matz, Jonathan , Lanser, Bruce J , Chong, Hey J , Rupp, Ned , Bird, J Andrew , Muraro, Antonella , Leonard, Stephanie , Carr, Warner W , Chinthrajah, Sharon , Sharma, Hemant P , Burks, A Wesley , Leickly, Frederick E , Dorsey, Morna J , Kachru, Rita , Fleischer, David M , Sher, Ellen , Portnoy, Jay M , Tsoumani, Marina , Johnston, Douglas T , Lieberman, Jay A , Zielen, Stefan , Anagnostou, Aikaterini , Varshney, Pooja , Wang, Julie , Hourihane, Jonathan O , du Toit, George , Oude Elberink, Hanneke N G , Casale, Thomas B , Nilsson, Caroline , Windom, Hugh H , Pongracic, Jacqueline A , Zubeldia, José M , Fritz, Stephen B , Vickery, Brian P , Dubois, Anthony E J , Vereda, Andrea , Rachid, Rima , Fernández-Rivas, Montserrat , Tilles, Stephen , Carr, Tara F , Siri, Dareen , Greos, Leon , Wood, Robert A , Sharma, Vibha , Ben-Shoshan, Moshe , Marcantonio, Annette , Hampel, Jr, Frank C , Shreffler,

in Administration, Oral / Adolescent / Adolescents / Adult / Adults / Age / Age Factors / Allergens - administration & dosage / Allergens - adverse effects / Arachis - adverse effects / Biological Products - administration & dosage / Biological Products - adverse effects / Biological Products - immunology / Child / Child, Preschool / Children / Desensitization, Immunologic - adverse effects / Desensitization, Immunologic - methods / Dose-Response Relationship, Immunologic / Double-Blind Method / Female / Food allergies / Gastrointestinal Diseases - etiology / Humans / Immunotherapy / Male / Middle Aged / Peanut Hypersensitivity - therapy / Peanuts / Pediatrics / Plant Proteins - administration & dosage / Plant Proteins - adverse effects / Plant Proteins - immunology / Young Adult

2018

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AR101 Oral Immunotherapy for Peanut Allergy

2018

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2018

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Journal Article

AR101 Oral Immunotherapy for Peanut Allergy

Ohayon, Jason,

Adelman, Daniel C,

Yang, William H,

Cheema, Amarjit,

Sanders, Georgiana M,

Zawadzki, Rezi,

Sher, Lawrence,

Spergel, Jonathan M,

Beyer, Kirsten,

Stillerman, Allan,

Ciaccio, Christina E,

Jeong, David K,

Jones, Stacie M,

Kim, Edwin H,

Mansfield, Lyndon E,

Matz, Jonathan,

Lanser, Bruce J,

Chong, Hey J,

Rupp, Ned,

Bird, J Andrew,

Muraro, Antonella,

Leonard, Stephanie,

Carr, Warner W,

Chinthrajah, Sharon,

Sharma, Hemant P,

Burks, A Wesley,

Leickly, Frederick E,

Dorsey, Morna J,

Kachru, Rita,

Fleischer, David M,

Sher, Ellen,

Portnoy, Jay M,

Tsoumani, Marina,

Johnston, Douglas T,

Lieberman, Jay A,

Zielen, Stefan,

Anagnostou, Aikaterini,

Varshney, Pooja,

Wang, Julie,

Hourihane, Jonathan O,

du Toit, George,

Oude Elberink, Hanneke N G,

Casale, Thomas B,

Nilsson, Caroline,

Windom, Hugh H,

Pongracic, Jacqueline A,

Zubeldia, José M,

Fritz, Stephen B,

Vickery, Brian P,

Dubois, Anthony E J,

Vereda, Andrea,

Rachid, Rima,

Fernández-Rivas, Montserrat,

Tilles, Stephen,

Carr, Tara F,

Siri, Dareen,

Greos, Leon,

Wood, Robert A,

Sharma, Vibha,

Ben-Shoshan, Moshe,

Marcantonio, Annette,

Hampel, Jr, Frank C,

Shreffler,

2018

Overview

A peanut-derived protein product, AR101, used in an oral desensitization protocol in children and adolescents with severe peanut allergy increased the amount of oral peanut protein tolerated in approximately two thirds of participants who received AR101, as compared with 1 of 25 controls.

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Publisher

Massachusetts Medical Society

Subject

Administration, Oral

/ Adolescent

/ Adolescents

/ Adult

/ Adults

/ Age

/ Age Factors