Journal Article

Postnatal Lifestyle Intervention for Overweight Women With Previous Gestational Diabetes: A Randomized Controlled Trial

Wotherspoon, Amy C, Holmes, Valerie A, Patterson, Chris C, McConnell, Mae, McCance, David R, Draffin, Claire R, Francis, Loraine, Irwin, Joanne, Brennan, Sarah F, McSorley, Oonagh, Davies, Mark, Farrell, Brid

2018

Overview

Gestational diabetes mellitus (GDM) is associated with a sevenfold increased lifetime risk of type 2 diabetes. Excessive gestational weight gain and postpartum weight retention are established predictors of long-term obesity. To determine the impact of a postnatal lifestyle intervention program for overweight women with previous gestational diabetes mellitus (PAIGE). Postnatal overweight women with previous GDM participated in a multicenter randomized controlled trial between June 2013 and December 2014. The intervention comprised a 1-hour educational program, a free 3-month referral to a commercial weight management organization (Slimming World), a pedometer, and structured telephone and text support, in addition to usual care. The control group received usual care only. The primary outcome was weight loss at 6 months. Sixty women were randomized (29 intervention; 31 control) in two centers based on their week of attendance. The intervention group demonstrated significant weight loss at 6 months after randomization compared with the control group: mean ±SD, 3.9 ± 7.0 kg vs 0.7 ±3.8 kg (P = 0.02). Blood glucose levels did not significantly differ. With respect to well-being measures, a bodily pain was significantly reduced in the intervention group (P = 0.007). PAIGE resulted in significantly greater weight loss at 6 months compared with usual care. Such weight loss could prove beneficial in terms of better long-term health and subsequent prevention of type 2 diabetes in overweight women with previous GDM. Future interventions must consider recruitment strategies, timing of the intervention, and inclusion of partners and/or other family members.

• Publisher: Copyright Oxford University Press,Oxford University Press
• Subject: Adult / Blood glucose / Body weight / Body weight loss / Care and treatment / Clinical trials / Diabetes / Diabetes mellitus / Diabetes mellitus (non-insulin dependent) / Diabetes therapy / Diabetes, Gestational / Female / Gestational diabetes / Glucose / Health aspects / Humans / Intervention / Lifestyles / Obesity / Obesity - complications / Obesity - therapy / Overweight / Overweight - complications / Overweight - therapy / Overweight persons / Pain management / Patient outcomes / Postnatal care / Postpartum / Postpartum Period / Pregnancy / Pregnant women / Risk Reduction Behavior / Treatment Outcome / Type 2 diabetes / Weight control / Weight Gain / Weight Loss / Weight Reduction Programs - methods / Well being