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R/qtl2: Software for Mapping Quantitative Trait Loci with High-Dimensional Data and Multiparent Populations
by
Furlotte, Nicholas A
, Prins, Pjotr
, Sen, Śaunak
, Churchill, Gary A
, Broman, Karl W
, Simecek, Petr
, Gatti, Daniel M
, Yandell, Brian S
in
Animals
/ Chromosome Mapping - methods
/ Collaboration
/ Computer programs
/ Design
/ Freeware
/ Gene expression
/ Gene mapping
/ Genetics
/ Genome-Wide Association Study - methods
/ Genomes
/ Genotype & phenotype
/ Genotyping
/ Genotyping Techniques - methods
/ Haplotypes
/ Investigations
/ Mapping
/ Mice
/ Nematodes
/ Open source software
/ Phenotypes
/ Plant populations
/ Population
/ Population structure
/ Populations
/ Programming languages
/ Proteomics
/ Quantitative Trait Loci
/ Single-nucleotide polymorphism
/ Software
2019
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R/qtl2: Software for Mapping Quantitative Trait Loci with High-Dimensional Data and Multiparent Populations
by
Furlotte, Nicholas A
, Prins, Pjotr
, Sen, Śaunak
, Churchill, Gary A
, Broman, Karl W
, Simecek, Petr
, Gatti, Daniel M
, Yandell, Brian S
in
Animals
/ Chromosome Mapping - methods
/ Collaboration
/ Computer programs
/ Design
/ Freeware
/ Gene expression
/ Gene mapping
/ Genetics
/ Genome-Wide Association Study - methods
/ Genomes
/ Genotype & phenotype
/ Genotyping
/ Genotyping Techniques - methods
/ Haplotypes
/ Investigations
/ Mapping
/ Mice
/ Nematodes
/ Open source software
/ Phenotypes
/ Plant populations
/ Population
/ Population structure
/ Populations
/ Programming languages
/ Proteomics
/ Quantitative Trait Loci
/ Single-nucleotide polymorphism
/ Software
2019
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R/qtl2: Software for Mapping Quantitative Trait Loci with High-Dimensional Data and Multiparent Populations
by
Furlotte, Nicholas A
, Prins, Pjotr
, Sen, Śaunak
, Churchill, Gary A
, Broman, Karl W
, Simecek, Petr
, Gatti, Daniel M
, Yandell, Brian S
in
Animals
/ Chromosome Mapping - methods
/ Collaboration
/ Computer programs
/ Design
/ Freeware
/ Gene expression
/ Gene mapping
/ Genetics
/ Genome-Wide Association Study - methods
/ Genomes
/ Genotype & phenotype
/ Genotyping
/ Genotyping Techniques - methods
/ Haplotypes
/ Investigations
/ Mapping
/ Mice
/ Nematodes
/ Open source software
/ Phenotypes
/ Plant populations
/ Population
/ Population structure
/ Populations
/ Programming languages
/ Proteomics
/ Quantitative Trait Loci
/ Single-nucleotide polymorphism
/ Software
2019
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R/qtl2: Software for Mapping Quantitative Trait Loci with High-Dimensional Data and Multiparent Populations
Journal Article
R/qtl2: Software for Mapping Quantitative Trait Loci with High-Dimensional Data and Multiparent Populations
2019
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Overview
R/qtl2 is an interactive software environment for mapping quantitative trait loci (QTL) in experimental populations. The R/qtl2 software expands the scope of the widely-used R/qtl software package to include multiparental populations, better handles modern high-dimensional data...
R/qtl2 is an interactive software environment for mapping quantitative trait loci (QTL) in experimental populations. The R/qtl2 software expands the scope of the widely used R/qtl software package to include multiparent populations derived from more than two founder strains, such as the Collaborative Cross and Diversity Outbred mice, heterogeneous stocks, and MAGIC plant populations. R/qtl2 is designed to handle modern high-density genotyping data and high-dimensional molecular phenotypes, including gene expression and proteomics. R/qtl2 includes the ability to perform genome scans using a linear mixed model to account for population structure, and also includes features to impute SNPs based on founder strain genomes and to carry out association mapping. The R/qtl2 software provides all of the basic features needed for QTL mapping, including graphical displays and summary reports, and it can be extended through the creation of add-on packages. R/qtl2, which is free and open source software written in the R and C++ programming languages, comes with a test framework.
Publisher
Genetics Society of America
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