Journal Article

Glycemic Analysis and Stratification of Pediatric Patients with Type 1 Diabetes Using isCGM in Southern Spain: Insights from the Andiacare Digital Platform

Leiva-Gea, Isabel, Ariza-Jiménez, Ana Belén, Romero-Pérez, María del Mar, Rodríguez de Vera-Gómez, Pablo, Moreno-Jabato, Fernando, Fernández-Hernández, Eugenio, Calleja Cabeza, Patricia, Santos Mata, María Ángeles, Lechuga-Sancho, Alfonso María, Mier-Palacios, Mercedes, Vivas-González, Gustavo, Guarino-Narváez, Jessica, Jiménez-Martín, Ana Pilar, Momblan, Jerónimo, Ranchal-Pérez, María del Pilar, Gómez-Vida, José María, Gómez-Perea, Ana, Martínez-Moya, Gabriela, Martínez-Brocca, María Asunción, Lendínez-Jurado, Alfonso, García-García, Emilio

2025

Overview

Background/Objectives: Type 1 diabetes mellitus (T1D) is the most common metabolic disorder in children, with significant physical and emotional impacts. Achieving optimal glucometric control is challenging due to the complex management and limitations of insulin therapy. Advances in pharmacology and technology, including continuous glucose monitoring (CGM) systems, offer new options for diabetes management. We developed Andiacare, an open-source platform for macro/micro-management of diabetes and analyzed its application in a pediatric T1D cohort to evaluate glucometric control patterns. Methods: A retrospective cohort study was conducted in a pediatric population (<18 years old) in Andalusia, Spain. Patients treated with Multiple Daily Injections of Insulin (MDI) and FreeStyle Libre 2 System (Abbott, Spain) were included. The patient data were analyzed using the Andiacare platform, which categorizes patients based on the Advanced Technologies and Treatments for Diabetes (ATTD) panel’s targets for glucometric control. Results: The study included 2215 patients from 18 pediatric hospitals. The Andiacare platform categorized patients into four groups based on glucometric control parameters, enabling patient stratification based on their glucometric control. Only 25.8% of the cohort achieved the recommended Time in Range (TIR), and 9.5% of the patients achieved all target parameters of glucometric control. Age is a determinant factor in adherence and achievement of set goals. Conclusions: This study offers insights into glucometric control in a large pediatric population with T1D in Andalusia. Few patients achieved the recommended glucometric control targets, highlighting the need for improved management strategies. The use of digital platforms such as Andiacare might contribute to facilitating the management of large pediatric cohorts. New algorithms integrating glucometric and non-glucometric parameters are required for improved individual and cohort categorization to optimize therapeutic interventions.

• Publisher: MDPI AG,Multidisciplinary Digital Publishing Institute (MDPI)
• Subject: Algorithms / Analysis / Blood sugar monitoring / Care and treatment / Clinical medicine / Computer platforms / Demographic aspects / Diabetes / Diagnosis / Exercise / Glucose monitoring / Health aspects / Hyperglycemia / Hypoglycemia / Insulin / Medical personnel / Metabolism / Patients / Pediatrics / Professional ethics / Sensors / Type 1 diabetes / Young adults