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A Decade of Antifungal Leads from Natural Products: 2010–2019
by
Le Pape, Patrice
, Ourliac-Garnier, Isabelle
, Ganesan, A.
, Marchand, Pascal
, Aldholmi, Mohammed
in
Alzheimer's disease
/ Antifungal agents
/ Bacteria
/ Biological activity
/ Biosynthesis
/ Enzymes
/ FDA approval
/ Fermentation
/ Fungal infections
/ Fungi
/ Gram-positive bacteria
/ Human health and pathology
/ Immune system
/ Life Sciences
/ Metabolites
/ Mutation
/ Natural products
/ Pathogens
/ Peptides
/ Pharmacokinetics
/ Regulatory approval
/ Review
/ Tropical diseases
2019
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A Decade of Antifungal Leads from Natural Products: 2010–2019
by
Le Pape, Patrice
, Ourliac-Garnier, Isabelle
, Ganesan, A.
, Marchand, Pascal
, Aldholmi, Mohammed
in
Alzheimer's disease
/ Antifungal agents
/ Bacteria
/ Biological activity
/ Biosynthesis
/ Enzymes
/ FDA approval
/ Fermentation
/ Fungal infections
/ Fungi
/ Gram-positive bacteria
/ Human health and pathology
/ Immune system
/ Life Sciences
/ Metabolites
/ Mutation
/ Natural products
/ Pathogens
/ Peptides
/ Pharmacokinetics
/ Regulatory approval
/ Review
/ Tropical diseases
2019
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A Decade of Antifungal Leads from Natural Products: 2010–2019
by
Le Pape, Patrice
, Ourliac-Garnier, Isabelle
, Ganesan, A.
, Marchand, Pascal
, Aldholmi, Mohammed
in
Alzheimer's disease
/ Antifungal agents
/ Bacteria
/ Biological activity
/ Biosynthesis
/ Enzymes
/ FDA approval
/ Fermentation
/ Fungal infections
/ Fungi
/ Gram-positive bacteria
/ Human health and pathology
/ Immune system
/ Life Sciences
/ Metabolites
/ Mutation
/ Natural products
/ Pathogens
/ Peptides
/ Pharmacokinetics
/ Regulatory approval
/ Review
/ Tropical diseases
2019
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A Decade of Antifungal Leads from Natural Products: 2010–2019
Journal Article
A Decade of Antifungal Leads from Natural Products: 2010–2019
2019
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Overview
In this review, we discuss novel natural products discovered within the last decade that are reported to have antifungal activity against pathogenic species. Nearly a hundred natural products were identified that originate from bacteria, algae, fungi, sponges, and plants. Fungi were the most prolific source of antifungal compounds discovered during the period of review. The structural diversity of these antifungal leads encompasses all the major classes of natural products including polyketides, shikimate metabolites, terpenoids, alkaloids, and peptides.
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