Asset Details
Do you wish to reserve the book?
Current and future status of JAK inhibitors
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Current and future status of JAK inhibitors
Do you wish to request the book?
Current and future status of JAK inhibitors
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Current and future status of JAK inhibitors
2021
Overview
An enhanced understanding of the importance of Janus kinase (JAK) and signal transducer and activator of transcription (STAT) signalling in multiple disease states has led to an increasing applicability of therapeutic intervention with JAK inhibitors. These agents have revolutionised treatments for a heterogeneous group of disorders, such as myeloproliferative neoplasms, rheumatoid arthritis, inflammatory bowel disease, and multiple immune-driven dermatological diseases, exemplifying rapid bench-to-bedside translation. In this Therapeutics paper, we summarise the currently available data concerning the successes and safety of an array of JAK inhibitors and hypothesise on how these fields could develop.
Publisher
Elsevier Ltd,Elsevier Limited
Subject
/ Arthritis, Rheumatoid - drug therapy
/ Humans
/ Inflammatory Bowel Diseases - drug therapy
/ Janus Kinase Inhibitors - therapeutic use
/ Kinases
/ Lymphoma
/ Mutation
/ Myeloproliferative Disorders - drug therapy
/ Oncology
/ Piperidines - therapeutic use
/ Protein Kinase Inhibitors - therapeutic use
/ Pyrimidines - therapeutic use
/ Pyrrolidines - therapeutic use
/ Signal Transduction - drug effects
/ Sulfonamides - therapeutic use
/ Tumors
