Asset Details
Do you wish to reserve the book?
Building capacity for sickle cell stroke prevention in low-resource settings
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Building capacity for sickle cell stroke prevention in low-resource settings
Do you wish to request the book?
Building capacity for sickle cell stroke prevention in low-resource settings
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Building capacity for sickle cell stroke prevention in low-resource settings
2025
Overview
Background
Sickle cell anemia is an inherited hematological disease with significant morbidity and mortality, particularly in resource-limited settings. Stroke is preventable through transcranial Doppler ultrasonography screening, identifying high-risk children for preventive hydroxyurea treatment.
Objectives
Describe how public health leaders can mitigate stroke risk in sub-Saharan Africa through ultrasonography training and supervision. Secondary objectives included describing operational and systemic factors influencing training and implementation in these settings; exploring leadership skills to improve clinical care; assessing technology and knowledge transfer as drivers of stroke screening and prevention; and providing recommendations for stroke screening in the context of safe, effective, and culturally-appropriate care, including disease-modifying hydroxyurea therapy.
Methods
We used a qualitative design with 17 semi-structured interviews of examiners and stakeholders from six countries across sub-Saharan Africa. Interviews were coded and analyzed using Grounded Theory to identify effective training and program strategies and develop a capacity-building model supporting stroke prevention.
Results
In-person training with African examiners was preferred over web-based platforms, and ongoing training, supervision, and support through United States-African collaborations increased skill development. Participants described the major clinical and socioeconomic impacts of sickle cell anemia on children, families and communities and emphasized the role of hydroxyurea to prevent complications and decrease health system burden.
Conclusions
A multifaceted approach to sickle cell capacity building with education, policy development, training, and hydroxyurea offers a holistic approach that leverages geographical partnerships and builds on existing resources in sub-Saharan Africa to provide safe, effective, and sustainable care that improves outcomes for children worldwide.
Publisher
BioMed Central,Nature Publishing Group,Springer
Subject
