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High Inhibition Activity of CQDs-Macaranga tanarius Organic Framework Nanomaterial-Based Antibacterials
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Journal Article
High Inhibition Activity of CQDs-Macaranga tanarius Organic Framework Nanomaterial-Based Antibacterials
2024
Overview
Antibacterial agent based on modification of
Macaranga tanarius
(
M. tanarius
) extract into CQDs@
M. tanarius
has been successfully synthesized and applied against
Escherichia coli
and
Staphylococcus aureus
.
Macaranga tanarius
plants were obtained from Buton Island, Southeast Sulawesi-Indonesia, and used as precursors for Carbon Quantum Dots (CQDs). In the synthesis, the dried leaves of
M. tanarius
were macerated, and then the filtrate was modified hydrothermally in a Teflon-lined stainless steel autoclave. The modification results produce nano-sized CQDs@
M. tanarius
particles. The PSA test confirmed this, which described the CQDs@
M. tanarius
particle size as 57.0 nm. The results of UV–Vis spectroscopy tests illustrate that the CQDs@
M. tanarius
molecules experience π → π* and n → π* electronic transitions at a wavelength of 367 nm. Meanwhile, in the FTIR spectroscopy test, stretching vibrations from the functional groups –OH, C–H, C=O, C–O, and the benzene ring were observed at wave numbers 3415.93 cm
−1
, 2976.16 cm
−1
, 1641.42 cm
−1
, 1274.95 cm
−1
, and 692.44 cm
−1
, respectively. Based on the antibacterial activity test, it is known that CQDs@
M. tanarius
has high inhibitory activity against
E. coli
and
S. aureus
. The resulting inhibition diameters are 15.82 mm and 11.24 mm, respectively. This high inhibitory diameter further illustrates the potential of CQDs@
M. tanarius
for its further application as an antibacterial material in the future.
Publisher
Springer India,Springer Nature B.V
