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The many faces of filamin: A versatile molecular scaffold for cell motility and signalling
by
Feng, Yuanyi
, Walsh, Christopher A.
in
Binding proteins
/ Biomedical and Life Sciences
/ Brain - abnormalities
/ Cancer Research
/ Cell Biology
/ Cell Movement
/ Cells
/ Contractile Proteins - genetics
/ Contractile Proteins - metabolism
/ Contractile Proteins - physiology
/ Developmental Biology
/ Female
/ Filamins
/ Gene expression
/ Humans
/ Life Sciences
/ Male
/ Microfilament Proteins - genetics
/ Microfilament Proteins - metabolism
/ Microfilament Proteins - physiology
/ Motility
/ Mutation
/ Mutation, Missense
/ Physiological aspects
/ Proteins
/ review-article
/ Signal Transduction
/ Stem Cells
2004
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The many faces of filamin: A versatile molecular scaffold for cell motility and signalling
by
Feng, Yuanyi
, Walsh, Christopher A.
in
Binding proteins
/ Biomedical and Life Sciences
/ Brain - abnormalities
/ Cancer Research
/ Cell Biology
/ Cell Movement
/ Cells
/ Contractile Proteins - genetics
/ Contractile Proteins - metabolism
/ Contractile Proteins - physiology
/ Developmental Biology
/ Female
/ Filamins
/ Gene expression
/ Humans
/ Life Sciences
/ Male
/ Microfilament Proteins - genetics
/ Microfilament Proteins - metabolism
/ Microfilament Proteins - physiology
/ Motility
/ Mutation
/ Mutation, Missense
/ Physiological aspects
/ Proteins
/ review-article
/ Signal Transduction
/ Stem Cells
2004
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Do you wish to request the book?
The many faces of filamin: A versatile molecular scaffold for cell motility and signalling
by
Feng, Yuanyi
, Walsh, Christopher A.
in
Binding proteins
/ Biomedical and Life Sciences
/ Brain - abnormalities
/ Cancer Research
/ Cell Biology
/ Cell Movement
/ Cells
/ Contractile Proteins - genetics
/ Contractile Proteins - metabolism
/ Contractile Proteins - physiology
/ Developmental Biology
/ Female
/ Filamins
/ Gene expression
/ Humans
/ Life Sciences
/ Male
/ Microfilament Proteins - genetics
/ Microfilament Proteins - metabolism
/ Microfilament Proteins - physiology
/ Motility
/ Mutation
/ Mutation, Missense
/ Physiological aspects
/ Proteins
/ review-article
/ Signal Transduction
/ Stem Cells
2004
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The many faces of filamin: A versatile molecular scaffold for cell motility and signalling
Journal Article
The many faces of filamin: A versatile molecular scaffold for cell motility and signalling
2004
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Overview
Filamins were discovered as the first family of non-muscle actin-binding protein. They are lage cytoplasmic proteins that cross-link cortical actin into a dynamic three-dimensional structure. Filamins have also been reported to interact with a large number of cellular proteins of great functional diversity, suggesting that they are unusually versatile signalling scaffolds. More recently, genetic mutations in filamin A and B have been reported to cause a wide range of human diseases, suggesting that different diseases highlight distinct filamin interactions.
Publisher
Nature Publishing Group UK,Nature Publishing Group
Subject
/ Biomedical and Life Sciences
/ Cells
/ Contractile Proteins - genetics
/ Contractile Proteins - metabolism
/ Contractile Proteins - physiology
/ Female
/ Filamins
/ Humans
/ Male
/ Microfilament Proteins - genetics
/ Microfilament Proteins - metabolism
/ Microfilament Proteins - physiology
/ Motility
/ Mutation
/ Proteins
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