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Genomic Analysis of Lassa Virus during an Increase in Cases in Nigeria in 2018

by Gaye, Amy , Kotliar, Dylan , Muoebonam, Ekene B , Enigbe, Rachael , Wohl, Shirlee , Andersen, Kristian G , Iruolagbe, Christopher , Siddle, Katherine J , Qu, James , Nekoui, Mahan , MacInnis, Bronwyn L , Happi, Christian T , Freije, Catherine A , Folarin, Onikepe A , Uyigue, Eghosa , Ye, Simon , Kayode, Tolulope , Gladden-Young, Adrianne , Winnicki, Sarah M , Park, Daniel J , Akhilomen, Patience , Shah, Rickey R , Ihekweazu, Chikwe , Carter, Amber , Okonofua, Grace , Osiemi, Blessing , Barnes, Kayla G , Mehta, Samar , Uwanibe, Jessica , Nosamiefan, Iguosadolo , Brehio, Patrick , Momoh, Mambu , Ogbaini-Emovon, Ephraim , Tomori, Oyewale , Oguzie, Judith U , Ajogbasile, Fehintola , Aiyepada, John , Oluniyi, Paul , Okogbenin, Sylvanus , Odia, Ikponmwosa , Airende, Michael , Garry, Robert F , Omoregie, Omigie , Yozwiak, Nathan L , Akpede, George , Schaffner, Stephen F , Ebo, Benevolence , Eromon, Philomena , Chak, Bridget , Sabeti, Pardis C , Okokhere, Peter O

in Adolescent / Adult / Animals / Bayes Theorem / Deoxyribonucleic acid / Disease control / Disease Reservoirs / DNA / Epidemics / Female / Fever / Genetic Variation / Genome, Viral / Genomes / Genomic analysis / Genomics / Geography / Humans / Infectious diseases / Laboratories / Lassa fever / Lassa Fever - epidemiology / Lassa Fever - transmission / Lassa Fever - virology / Lassa virus - genetics / Male / Markov Chains / Medicine / Middle Aged / Migration / Nigeria - epidemiology / Phylogeny / Phylogeography / Public health / R&D / Research & development / Rivers / RNA, Viral - analysis / Rodentia / Seasons / Sequence Analysis, RNA / Teaching hospitals / Viral infections / Zoonoses - transmission

2018

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Genomic Analysis of Lassa Virus during an Increase in Cases in Nigeria in 2018

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Genomic Analysis of Lassa Virus during an Increase in Cases in Nigeria in 2018

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Journal Article

Genomic Analysis of Lassa Virus during an Increase in Cases in Nigeria in 2018

Gaye, Amy,

Kotliar, Dylan,

Muoebonam, Ekene B,

Enigbe, Rachael,

Wohl, Shirlee,

Andersen, Kristian G,

Iruolagbe, Christopher,

Siddle, Katherine J,

Qu, James,

Nekoui, Mahan,

MacInnis, Bronwyn L,

Happi, Christian T,

Freije, Catherine A,

Folarin, Onikepe A,

Uyigue, Eghosa,

Ye, Simon,

Kayode, Tolulope,

Gladden-Young, Adrianne,

Winnicki, Sarah M,

Park, Daniel J,

Akhilomen, Patience,

Shah, Rickey R,

Ihekweazu, Chikwe,

Carter, Amber,

Okonofua, Grace,

Osiemi, Blessing,

Barnes, Kayla G,

Mehta, Samar,

Uwanibe, Jessica,

Nosamiefan, Iguosadolo,

Brehio, Patrick,

Momoh, Mambu,

Ogbaini-Emovon, Ephraim,

Tomori, Oyewale,

Oguzie, Judith U,

Ajogbasile, Fehintola,

Aiyepada, John,

Oluniyi, Paul,

Okogbenin, Sylvanus,

Odia, Ikponmwosa,

Airende, Michael,

Garry, Robert F,

Omoregie, Omigie,

Yozwiak, Nathan L,

Akpede, George,

Schaffner, Stephen F,

Ebo, Benevolence,

Eromon, Philomena,

Chak, Bridget,

Sabeti, Pardis C,

Okokhere, Peter O

2018

Overview

An increase in Lassa fever cases was identified in Nigeria this year. In this analysis of the infecting viruses, the predominant mode of transmission appeared to be multiple insertions from local rodent populations rather than sustained person-to-person spread.

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Publisher

Massachusetts Medical Society

Subject

Adolescent

/ Adult

/ Animals

/ Bayes Theorem

/ Deoxyribonucleic acid

/ Disease control

/ Disease Reservoirs