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Extended Reduced-Dose Apixaban for Cancer-Associated Venous Thromboembolism

by Szmit, Sebastian , Grange, Claire , Yeo, Erik , Westerweel, Peter , Monreal, Manuel , Klok, Frederikus A. , Laporte, Silvy , Le Gal, Grégoire , Chapelle, Céline , Bertoletti, Laurent , Sanchez, Olivier , López-Núñez, Juan J. , Cohen, Alexander T. , Meyer, Guy , Huisman, Menno V. , Otero-Candelera, Remedios , Ay, Cihan , Girard, Philippe , Carrier, Marc , Mismetti, Patrick , Mahé, Isabelle , Robert-Ebadi, Helia , Righini, Marc , Bamias, Aristotelis , Syrigos, Kostas , Maraveyas, Anthony , Verhamme, Peter , Vicaut, Eric , Couturaud, Francis , Becattini, Cecilia , Torbicki, Adam , Agnelli, Giancarlo , Falvo, Nicolas , Mayeur, Didier , Chidiac, Jean

in Administration, Oral / Aged / Anticoagulants / Anticoagulation / Bleeding / Cancer / Cardiology / Cardiology General / Clinical medicine / Clinical practice guidelines / Coagulation / Critical Care / Critical Care General / Dose-Response Relationship, Drug / Double-Blind Method / Drug Administration Schedule / Embolism / Factor Xa Inhibitors - administration & dosage / Factor Xa Inhibitors - adverse effects / Female / Hematology / Hemorrhage - chemically induced / Hemorrhage - epidemiology / Humans / Incidence / Life Sciences / Male / Methodology / Middle Aged / Neoplasms - complications / Neoplasms - drug therapy / Oncology / Oncology General / Pharmaceutical sciences / Pharmacology / Pulmonary / Pulmonary arteries / Pulmonary Embolism - drug therapy / Pulmonary Embolism - etiology / Pulmonary Embolism - prevention & control / Pulmonary embolisms / Pyrazoles - administration & dosage / Pyrazoles - adverse effects / Pyridones - administration & dosage / Pyridones - adverse effects / Recurrence / Statistics / Thromboembolism / Thrombosis / Veins & arteries / Venous Thrombosis - drug therapy / Venous Thrombosis - etiology

2025

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Extended Reduced-Dose Apixaban for Cancer-Associated Venous Thromboembolism

2025

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2025

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Journal Article

Extended Reduced-Dose Apixaban for Cancer-Associated Venous Thromboembolism

Szmit, Sebastian,

Grange, Claire,

Yeo, Erik,

Westerweel, Peter,

Monreal, Manuel,

Klok, Frederikus A.,

Laporte, Silvy,

Le Gal, Grégoire,

Chapelle, Céline,

Bertoletti, Laurent,

Sanchez, Olivier,

López-Núñez, Juan J.,

Cohen, Alexander T.,

Meyer, Guy,

Huisman, Menno V.,

Otero-Candelera, Remedios,

Ay, Cihan,

Girard, Philippe,

Carrier, Marc,

Mismetti, Patrick,

Mahé, Isabelle,

Robert-Ebadi, Helia,

Righini, Marc,

Bamias, Aristotelis,

Syrigos, Kostas,

Maraveyas, Anthony,

Verhamme, Peter,

Vicaut, Eric,

Couturaud, Francis,

Becattini, Cecilia,

Torbicki, Adam,

Agnelli, Giancarlo,

Falvo, Nicolas,

Mayeur, Didier,

Chidiac, Jean

2025

Overview

In a trial involving patients with active cancer and venous thromboembolism, extended anticoagulation with reduced-dose apixaban was noninferior to full-dose apixaban for preventing recurrent thromboembolic events.

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Publisher

Massachusetts Medical Society

Subject

/ Aged

/ Cancer