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Glycemic Control and Excess Mortality in Type 1 Diabetes
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Glycemic Control and Excess Mortality in Type 1 Diabetes
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Journal Article
Glycemic Control and Excess Mortality in Type 1 Diabetes
2014
Overview
In this study, patients with type 1 diabetes and a glycated hemoglobin level of 6.9% or lower (≤52 mmol per mole) were found to have a risk of death from any cause or from cardiovascular causes that was twice as high as that for matched controls.
Type 1 diabetes is associated with a substantially increased risk of premature death as compared with that in the general population.
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Among persons with diabetes who are younger than 30 years of age, excess mortality is largely explained by acute complications of diabetes, including diabetic ketoacidosis and hypoglycemia
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; cardiovascular disease is the main cause of death later in life.
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Improving glycemic control in patients with type 1 diabetes substantially reduces their risk of microvascular complications and cardiovascular disease.
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Accordingly, diabetes treatment guidelines emphasize good glycemic control,
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which is indicated by the glycated hemoglobin level, . . .
Publisher
Massachusetts Medical Society
Subject
/ Age
/ Biological and medical sciences
/ Cardiovascular Diseases - etiology
/ Cardiovascular Diseases - mortality
/ Death
/ Diabetes
/ Diabetes mellitus (insulin dependent)
/ Diabetes Mellitus, Type 1 - blood
/ Diabetes Mellitus, Type 1 - complications
/ Diabetes Mellitus, Type 1 - mortality
/ Diabetes. Impaired glucose tolerance
/ Endocrine pancreas. Apud cells (diseases)
/ Etiopathogenesis. Screening. Investigations. Target tissue resistance
/ Female
/ Glycated Hemoglobin A - metabolism
/ Humans
/ Male
/ Risk
