Asset Details
Do you wish to reserve the book?
Quality of Vitamin B12 Supplements Regarding Vitamin Assay and Content of Heavy Metals
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Quality of Vitamin B12 Supplements Regarding Vitamin Assay and Content of Heavy Metals
Do you wish to request the book?
Quality of Vitamin B12 Supplements Regarding Vitamin Assay and Content of Heavy Metals
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Quality of Vitamin B12 Supplements Regarding Vitamin Assay and Content of Heavy Metals
2025
Overview
Vegetarians must rely on supplements to meet the recommended daily intake of vitamin B12. Therefore, it is essential to establish a rapid, inexpensive, and reliable method of determining B12 levels in order to accurately characterize and assess the quality of supplements. This study describes a methodology for quantifying vitamin B12 in the form of methylcobalamin and cyanocobalamin following 2 min of ultrasound-assisted extraction performed at pH 4. Vitamin B12 was determined using UV-Vis spectrophotometry and liquid chromatography-tandem mass spectrometry. Thus, LC-MS/MS validated the cost-effective UV-Vis method. The content and form of vitamin B12 in the tested supplements were investigated, and serious discrepancies were found in the content or form of vitamin B12 in three out of ten supplements. To verify the quality of the analyzed supplements, the presence of metal impurities (as Cd, Hg, and Pb) was also assessed using high-resolution continuum source electrothermal atomic absorption spectrometry. No risk associated with the presence of these metals has been noted. Nevertheless, our findings underscore the need for stricter quality control in supplement manufacturing.
Publisher
MDPI AG
