Journal Article

A single transcription factor promotes both yield and immunity in rice

Zhou, Lian, Ronald, Pamela C., Li, Jiayang, Qing, Hai, Zhou, Jian-Min, Li, Weitao, Liu, Jiali, He, Min, Li, Yan, Wang, Yuping, Yin, Junjie, Chen, Xuewei, Wu, Xianjun, Li, Shigui, Wang, Jichun, Chern, Mawsheng, Shi, Hui, Li, Ping, Liu, Guifu, Yu, Hong, Wang, Jing, Chen, Xiaoqiong, Yi, Hong, Wang, Wenming, Zhu, Xiaobo, Zhu, Lihuang

2018

Overview

Plants that are fighting microbial pathogens often divert resources that could be used for growth into the immune response. For crops, this translates into lower yield when plant immunity is activated. Wang et al. show that, in rice, reversible phosphorylation of a key transcription factor allows the plant to defend against fungal attack when needed but then, within days, reallocate resources back to growth (see the Perspective by Greene and Dong). Thus, both pathogen defense and crop yield can be sustained. Science , this issue p. 1026 ; see also p. 976 A transcription factor that builds a high-yielding rice plant also supports immune responses. Plant immunity often penalizes growth and yield. The transcription factor Ideal Plant Architecture 1 (IPA1) reduces unproductive tillers and increases grains per panicle, which results in improved rice yield. Here we report that higher IPA1 levels enhance immunity. Mechanistically, phosphorylation of IPA1 at amino acid Ser 163 within its DNA binding domain occurs in response to infection by the fungus Magnaporthe oryzae and alters the DNA binding specificity of IPA1. Phosphorylated IPA1 binds to the promoter of the pathogen defense gene WRKY45 and activates its expression, leading to enhanced disease resistance. IPA1 returns to a nonphosphorylated state within 48 hours after infection, resuming support of the growth needed for high yield. Thus, IPA1 promotes both yield and disease resistance by sustaining a balance between growth and immunity.

• Publisher: The American Association for the Advancement of Science
• Subject: Amino acids / Binding / Crop yield / Deoxyribonucleic acid / Disease resistance / DNA / Fungi / Gene expression / Immune response / Immune system / Immunity / Microorganisms / Pathogens / Phosphorylation / Plant immunity / Resource Allocation / Rice / Tillers / Transcription factors