Journal Article

Plant extracts and natural compounds used against UVB-induced photoaging

Stuppner, Hermann, Waltenberger, Birgit, Jansen-Dürr, Pidder, Baraldo, Giorgia, Cavinato, Maria, Grade, Carla V. C.

2017

Overview

Skin is continuously exposed to a variety of environmental stresses, including ultraviolet (UV) radiation. UVB is an inherent component of sunlight that crosses the epidermis and reaches the upper dermis, leading to increased oxidative stress, activation of inflammatory response and accumulation of DNA damage among other effects. The increase in UVB radiation on earth due to the destruction of stratospheric ozone poses a major environmental threat to the skin, increasing the risk of damage with long-term consequences, such as photoaging and photocarcinogenesis. Extracts from plants and natural compounds have been historically used in traditional medicine in the form of teas and ointments but the effect of most of these compounds has yet to be verified. Regarding the increasing concern of the population with issues related to quality of life and appearance, the cosmetic market for anti-aging and photoprotective products based on natural compounds is continuously growing, and there is increasing requirement of expansion on research in this field. In this review we summarized the most current and relevant information concerning plant extracts and natural compounds that are able to protect or mitigate the deleterious effects caused by photoaging in different experimental models.

• Publisher: Springer Netherlands,Springer Nature B.V
• Subject: Accumulation / Acids / Aging / Animals / Antioxidants / Atmospheric ozone / Biological Products - pharmacology / Biological Products - toxicity / Biomedical and Life Sciences / Cell Biology / Collagen / Consumer goods / Cosmetics / Cosmetics - pharmacology / Cosmetics - toxicity / Cytokines / Deoxyribonucleic acid / Dermis / Developmental Biology / DNA / DNA damage / Epidermis / Fruits / Geriatrics/Gerontology / Humans / Inflammation / Kinases / Life Sciences / Market potential / Medicinal plants / Medicine / Models, Animal / Ointments / Older people / Oxidative stress / Ozone / Plant extracts / Plant Extracts - pharmacology / Plant Extracts - toxicity / Plant protection / Proteins / Quality of life / Radiation / Review / Review Article / Risk Assessment / Seeds / Senescence / Signal Transduction - drug effects / Signal Transduction - radiation effects / Skin / Skin - drug effects / Skin - metabolism / Skin - pathology / Skin - radiation effects / Skin Aging - drug effects / Sunlight / Sunlight - adverse effects / Traditional medicine / Tumor necrosis factor-TNF / Ultraviolet radiation / Ultraviolet Rays - adverse effects