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COVID-19 and Cancer Comorbidity: Therapeutic Opportunities and Challenges
by
Abdul, Bakrudeen AA
, Prathipati, Philip
, Gupta, Subash C.
, Durden, Donald L.
, Pandey, Manoj K.
, Pathania, Anup S.
, Katta, Santharam S.
, Challagundla, Kishore B.
, Chava, Srinivas
, Gangula, Pandu R.
, Byrareddy, Siddappa N.
in
Antineoplastic Agents - pharmacology
/ Antineoplastic Agents - therapeutic use
/ Cardiovascular disease
/ Comorbidity
/ Coronaviruses
/ COVID-19
/ COVID-19 - epidemiology
/ COVID-19 - immunology
/ COVID-19 - virology
/ COVID-19 Drug Treatment
/ Diabetes
/ Disease transmission
/ Drug Repositioning
/ Epidemics
/ Fatalities
/ Genome, Viral - genetics
/ Humans
/ Infections
/ Lung cancer
/ Medical research
/ Mutation
/ Neoplasms - drug therapy
/ Neoplasms - epidemiology
/ Pandemics
/ Pandemics - prevention & control
/ Pathogenesis
/ Pneumonia
/ Proteins
/ Review
/ RNA polymerase
/ SARS-CoV-2 - genetics
/ SARS-CoV-2 - immunology
/ Severe acute respiratory syndrome coronavirus 2
/ Signal Transduction - drug effects
/ Signal Transduction - genetics
/ Signal Transduction - immunology
/ Viruses
2021
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COVID-19 and Cancer Comorbidity: Therapeutic Opportunities and Challenges
by
Abdul, Bakrudeen AA
, Prathipati, Philip
, Gupta, Subash C.
, Durden, Donald L.
, Pandey, Manoj K.
, Pathania, Anup S.
, Katta, Santharam S.
, Challagundla, Kishore B.
, Chava, Srinivas
, Gangula, Pandu R.
, Byrareddy, Siddappa N.
in
Antineoplastic Agents - pharmacology
/ Antineoplastic Agents - therapeutic use
/ Cardiovascular disease
/ Comorbidity
/ Coronaviruses
/ COVID-19
/ COVID-19 - epidemiology
/ COVID-19 - immunology
/ COVID-19 - virology
/ COVID-19 Drug Treatment
/ Diabetes
/ Disease transmission
/ Drug Repositioning
/ Epidemics
/ Fatalities
/ Genome, Viral - genetics
/ Humans
/ Infections
/ Lung cancer
/ Medical research
/ Mutation
/ Neoplasms - drug therapy
/ Neoplasms - epidemiology
/ Pandemics
/ Pandemics - prevention & control
/ Pathogenesis
/ Pneumonia
/ Proteins
/ Review
/ RNA polymerase
/ SARS-CoV-2 - genetics
/ SARS-CoV-2 - immunology
/ Severe acute respiratory syndrome coronavirus 2
/ Signal Transduction - drug effects
/ Signal Transduction - genetics
/ Signal Transduction - immunology
/ Viruses
2021
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COVID-19 and Cancer Comorbidity: Therapeutic Opportunities and Challenges
by
Abdul, Bakrudeen AA
, Prathipati, Philip
, Gupta, Subash C.
, Durden, Donald L.
, Pandey, Manoj K.
, Pathania, Anup S.
, Katta, Santharam S.
, Challagundla, Kishore B.
, Chava, Srinivas
, Gangula, Pandu R.
, Byrareddy, Siddappa N.
in
Antineoplastic Agents - pharmacology
/ Antineoplastic Agents - therapeutic use
/ Cardiovascular disease
/ Comorbidity
/ Coronaviruses
/ COVID-19
/ COVID-19 - epidemiology
/ COVID-19 - immunology
/ COVID-19 - virology
/ COVID-19 Drug Treatment
/ Diabetes
/ Disease transmission
/ Drug Repositioning
/ Epidemics
/ Fatalities
/ Genome, Viral - genetics
/ Humans
/ Infections
/ Lung cancer
/ Medical research
/ Mutation
/ Neoplasms - drug therapy
/ Neoplasms - epidemiology
/ Pandemics
/ Pandemics - prevention & control
/ Pathogenesis
/ Pneumonia
/ Proteins
/ Review
/ RNA polymerase
/ SARS-CoV-2 - genetics
/ SARS-CoV-2 - immunology
/ Severe acute respiratory syndrome coronavirus 2
/ Signal Transduction - drug effects
/ Signal Transduction - genetics
/ Signal Transduction - immunology
/ Viruses
2021
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COVID-19 and Cancer Comorbidity: Therapeutic Opportunities and Challenges
Journal Article
COVID-19 and Cancer Comorbidity: Therapeutic Opportunities and Challenges
2021
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Overview
The coronavirus disease 2019 (COVID-19) is a viral disease caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that affects the respiratory system of infected individuals. COVID-19 spreads between humans through respiratory droplets produced when an infected person coughs or sneezes. The COVID-19 outbreak originated in Wuhan, China at the end of 2019. As of 29 Sept 2020, over 235 countries, areas or territories across the globe reported a total of 33,441,919 confirmed cases, and 1,003,497 confirmed deaths due to COVID-19. Individuals of all ages are at risk for infection, but in most cases disease severity is associated with age and pre-existing diseases that compromise immunity, like cancer. Numerous reports suggest that people with cancer can be at higher risk of severe illness and related deaths from COVID-19. Therefore, managing cancer care under this pandemic is challenging and requires a collaborative multidisciplinary approach for optimal care of cancer patients in hospital settings. In this comprehensive review, we discuss the impact of the COVID-19 pandemic on cancer patients, their care, and treatment. Further, this review covers the SARS-CoV-2 pandemic, genome characterization, COVID-19 pathophysiology, and associated signaling pathways in cancer, and the choice of anticancer agents as repurposed drugs for treating COVID-19.
Publisher
Ivyspring International Publisher Pty Ltd,Ivyspring International Publisher
Subject
Antineoplastic Agents - pharmacology
/ Antineoplastic Agents - therapeutic use
/ COVID-19
/ Diabetes
/ Humans
/ Mutation
/ Pandemics - prevention & control
/ Proteins
/ Review
/ Severe acute respiratory syndrome coronavirus 2
/ Signal Transduction - drug effects
/ Signal Transduction - genetics
/ Signal Transduction - immunology
/ Viruses
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