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The role of ubiquitination and deubiquitination in tumor invasion and metastasis
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The role of ubiquitination and deubiquitination in tumor invasion and metastasis
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Journal Article
The role of ubiquitination and deubiquitination in tumor invasion and metastasis
2022
Overview
Ubiquitination is vital for multiple cellular processes via dynamic modulation of proteins related to cell growth, proliferation, and survival. Of the ubiquitination system components, E3 ubiquitin ligases and deubiquitinases have the most prominent roles in modulating tumor metastasis. This review will briefly summarize the observations and underlying mechanisms of multiple E3 ubiquitin ligases and deubiquitinases to regulate tumor metastasis. Further, we will discuss the relationship and importance between ubiquitination components and tumor progression.
Publisher
Ivyspring International Publisher Pty Ltd,Ivyspring International Publisher
