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Pairing of integrins with ECM proteins determines migrasome formation
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Journal Article
Pairing of integrins with ECM proteins determines migrasome formation
2017
Overview
Dear Editor, Recently we reported the discovery of migrasome, a new organelle of migrating cells [1]. Migrasomes are large vesicles that grow on the tips or intersections of retraction fibers at the rear of migrating cells. Following cell migration, the retraction fibers eventually break and the migrasomes become detached. The migrasomes and their contents, including cytosolic components and vesi- cles of unknown origin, are released into the extracellu- lar space -- a process we named as migracytosis. We speculated that migracytosis may play important roles in cell-cell communication.
Publisher
Nature Publishing Group UK,Nature Publishing Group
Subject
