Journal Article

Two divergent haplotypes from a highly heterozygous lychee genome suggest independent domestication events for early and late-maturing cultivars

Albert, Victor A., Luo, Xinping, Zheng, Chunfang, Zhang, Yanqing, Chen, Houbin, Ou, Liangxi, Fu, Jiaxin, Wang, Jiabao, Liang, Xinming, Jiang, Zide, Chen, Chengjie, Peng, Hongxiang, Xia, Rui, Yan, Qian, Hu, Guibing, Feng, Junting, Zhang, Xingtan, Yao, Lixian, Sankoff, David, Li, Jiawei, Wei, Yongzan, Ming, Ray, Salojärvi, Jarkko, Sun, Jinhua, Huang, Xuming, Zheng, Jiakun, McHale, Leah K., Wu, Zhenxian, Wai, Ching Man, Liu, Wei, Xiang, Xu, Fan, Guangyi, Guyot, Romain, Liu, Chengming, Li, Huanling, Rolling, William, Chen, Jiezhen, Mai, Yingxiao, Tang, Haibao, Lai, Biao, Li, Jianguo, Liu, Xin, Lan, Tianying, Zhang, Jisen

2022

Overview

Lychee is an exotic tropical fruit with a distinct flavor. The genome of cultivar ‘Feizixiao’ was assembled into 15 pseudochromosomes, totaling ~470 Mb. High heterozygosity (2.27%) resulted in two complete haplotypic assemblies. A total of 13,517 allelic genes (42.4%) were differentially expressed in diverse tissues. Analyses of 72 resequenced lychee accessions revealed two independent domestication events. The extremely early maturing cultivars preferentially aligned to one haplotype were domesticated from a wild population in Yunnan, whereas the late-maturing cultivars that mapped mostly to the second haplotype were domesticated independently from a wild population in Hainan. Early maturing cultivars were probably developed in Guangdong via hybridization between extremely early maturing cultivar and late-maturing cultivar individuals. Variable deletions of a 3.7 kb region encompassed by a pair of CONSTANS -like genes probably regulate fruit maturation differences among lychee cultivars. These genomic resources provide insights into the natural history of lychee domestication and will accelerate the improvement of lychee and related crops. Two divergent haplotypes from a highly heterozygous lychee genome of the cultivar ‘Feizixiao’ and resequencing of 72 lychee accessions provide insights into the genome evolution and domestication history of lychee.

• Publisher: Nature Publishing Group US,Nature Publishing Group
• Subject: 631/208/212 / 631/208/2491 / Agriculture / Animal Genetics and Genomics / Biomedical and Life Sciences / Biomedicine / Cancer Research / China / CONSTANS LIKE gene / Crops, Agricultural - genetics / Cultivars / Domestication / Estimates / Evolution, Molecular / Flavors / Flow cytometry / Flowers - genetics / Food quality / Fruits / Gene Function / Genes / Genome, Plant / Genomes / Germplasm / Haplotypes / Heterozygosity / Heterozygote / Human Genetics / Hybridization / Litchi / Litchi - genetics / Litchi - growth & development / Molecular Sequence Annotation / Polymorphism, Single Nucleotide / Population / Sequence Analysis, DNA / Species Specificity