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Automatic structuring of radiology reports with on-premise open-source large language models
by
Laqua, Caroline
, Engelhardt, Sandy
, Kather, Jakob
, Pinto dos Santos, Daniel
, Foersch, Sebastian
, Woźnicki, Piotr
, Fiku, Ina
, D’Antonoli, Tugba Akinci
, Laqua, Fabian Christopher
, Hekalo, Amar
, Truhn, Daniel
, Baeßler, Bettina
in
Artificial intelligence
/ Automation
/ Bayesian analysis
/ Business metrics
/ Correlation coefficient
/ Correlation coefficients
/ Datasets
/ Diagnostic Radiology
/ English language
/ Humans
/ Imaging
/ Imaging Informatics and Artificial Intelligence
/ Internal Medicine
/ Interventional Radiology
/ Large Language Models
/ Markov chains
/ Mathematical models
/ Medicine
/ Medicine & Public Health
/ Neuroradiology
/ Pleural effusion
/ Privacy
/ Radiography
/ Radiography, Thoracic
/ Radiology
/ Radiology Information Systems
/ Retrospective Studies
/ Semantics
/ Statistical inference
/ Structured data
/ Ultrasound
/ Workflow
2025
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Automatic structuring of radiology reports with on-premise open-source large language models
by
Laqua, Caroline
, Engelhardt, Sandy
, Kather, Jakob
, Pinto dos Santos, Daniel
, Foersch, Sebastian
, Woźnicki, Piotr
, Fiku, Ina
, D’Antonoli, Tugba Akinci
, Laqua, Fabian Christopher
, Hekalo, Amar
, Truhn, Daniel
, Baeßler, Bettina
in
Artificial intelligence
/ Automation
/ Bayesian analysis
/ Business metrics
/ Correlation coefficient
/ Correlation coefficients
/ Datasets
/ Diagnostic Radiology
/ English language
/ Humans
/ Imaging
/ Imaging Informatics and Artificial Intelligence
/ Internal Medicine
/ Interventional Radiology
/ Large Language Models
/ Markov chains
/ Mathematical models
/ Medicine
/ Medicine & Public Health
/ Neuroradiology
/ Pleural effusion
/ Privacy
/ Radiography
/ Radiography, Thoracic
/ Radiology
/ Radiology Information Systems
/ Retrospective Studies
/ Semantics
/ Statistical inference
/ Structured data
/ Ultrasound
/ Workflow
2025
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Automatic structuring of radiology reports with on-premise open-source large language models
by
Laqua, Caroline
, Engelhardt, Sandy
, Kather, Jakob
, Pinto dos Santos, Daniel
, Foersch, Sebastian
, Woźnicki, Piotr
, Fiku, Ina
, D’Antonoli, Tugba Akinci
, Laqua, Fabian Christopher
, Hekalo, Amar
, Truhn, Daniel
, Baeßler, Bettina
in
Artificial intelligence
/ Automation
/ Bayesian analysis
/ Business metrics
/ Correlation coefficient
/ Correlation coefficients
/ Datasets
/ Diagnostic Radiology
/ English language
/ Humans
/ Imaging
/ Imaging Informatics and Artificial Intelligence
/ Internal Medicine
/ Interventional Radiology
/ Large Language Models
/ Markov chains
/ Mathematical models
/ Medicine
/ Medicine & Public Health
/ Neuroradiology
/ Pleural effusion
/ Privacy
/ Radiography
/ Radiography, Thoracic
/ Radiology
/ Radiology Information Systems
/ Retrospective Studies
/ Semantics
/ Statistical inference
/ Structured data
/ Ultrasound
/ Workflow
2025
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Automatic structuring of radiology reports with on-premise open-source large language models
Journal Article
Automatic structuring of radiology reports with on-premise open-source large language models
2025
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Overview
Objectives
Structured reporting enhances comparability, readability, and content detail. Large language models (LLMs) could convert free text into structured data without disrupting radiologists’ reporting workflow. This study evaluated an on-premise, privacy-preserving LLM for automatically structuring free-text radiology reports.
Materials and methods
We developed an approach to controlling the LLM output, ensuring the validity and completeness of structured reports produced by a locally hosted Llama-2-70B-chat model. A dataset with de-identified narrative chest radiograph (CXR) reports was compiled retrospectively. It included 202 English reports from a publicly available MIMIC-CXR dataset and 197 German reports from our university hospital. Senior radiologist prepared a detailed, fully structured reporting template with 48 question-answer pairs. All reports were independently structured by the LLM and two human readers. Bayesian inference (Markov chain Monte Carlo sampling) was used to estimate the distributions of Matthews correlation coefficient (MCC), with [−0.05, 0.05] as the region of practical equivalence (ROPE).
Results
The LLM generated valid structured reports in all cases, achieving an average MCC of 0.75 (94% HDI: 0.70–0.80) and F1 score of 0.70 (0.70–0.80) for English, and 0.66 (0.62–0.70) and 0.68 (0.64–0.72) for German reports, respectively. The MCC differences between LLM and humans were within ROPE for both languages: 0.01 (−0.05 to 0.07), 0.01 (−0.05 to 0.07) for English, and −0.01 (−0.07 to 0.05), 0.00 (−0.06 to 0.06) for German, indicating approximately comparable performance.
Conclusion
Locally hosted, open-source LLMs can automatically structure free-text radiology reports with approximately human accuracy. However, the understanding of semantics varied across languages and imaging findings.
Key Points
Question
Why has structured reporting not been widely adopted in radiology despite clear benefits and how can we improve this?
Findings
A locally hosted large language model successfully structured narrative reports, showing variation between languages and findings.
Critical relevance
Structured reporting provides many benefits, but its integration into the clinical routine is limited. Automating the extraction of structured information from radiology reports enables the capture of structured data while allowing the radiologist to maintain their reporting workflow.
Publisher
Springer Berlin Heidelberg,Springer Nature B.V
Subject
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