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![Anti-Inflammatory Potential of n-3 Polyunsaturated Fatty Acids Enriched Hen Eggs Consumption in Improving Microvascular Endothelial Function of Healthy Individuals-Clinical Trial](https://www.mbrl.ae/o/mbrl-theme/images/site-assets/generic/no-book-image.png)
Anti-Inflammatory Potential of n-3 Polyunsaturated Fatty Acids Enriched Hen Eggs Consumption in Improving Microvascular Endothelial Function of Healthy Individuals-Clinical Trial
by
Kolar, Luka
, Stupin, Marko
, Grčević, Manuela
, Šerić, Vatroslav
, Stupin, Ana
, Matić, Anita
, Mihalj, Martina
, Kolobarić, Nikolina
, Mihaljević, Zrinka
, Šušnjara, Petar
, Kralik, Zlata
, Jukić, Ivana
, Kralik, Gordana
, Drenjančević, Ines
in
Acetylcholine
/ Activation
/ Adult
/ Animals
/ Anti-inflammatory agents
/ Anti-Inflammatory Agents - analysis
/ Anti-Inflammatory Agents - chemistry
/ Anti-Inflammatory Agents - pharmacology
/ Anti-Inflammatory Agents, Non-Steroidal - chemistry
/ Anti-Inflammatory Agents, Non-Steroidal - pharmacology
/ Atherosclerosis
/ Blood Chemical Analysis
/ Blood flow
/ Blood pressure
/ Body composition
/ Body composition (biology)
/ Body Composition - drug effects
/ Body fat
/ Body fluids
/ Body water
/ Chickens
/ Cholesterol
/ Consumption
/ Cytokines - blood
/ Doppler effect
/ Eggs
/ Eggs - analysis
/ Endothelium
/ Endothelium, Vascular - drug effects
/ Endothelium, Vascular - physiology
/ Enrichment
/ Fatty acids
/ Fatty Acids - blood
/ Fatty Acids, Omega-3 - analysis
/ Fatty Acids, Omega-3 - chemistry
/ Fatty Acids, Omega-3 - pharmacology
/ Female
/ Food
/ Food, Fortified
/ Functional foods & nutraceuticals
/ Growth factors
/ Hemodynamics - drug effects
/ Humans
/ Inflammation
/ Interferon
/ Interleukin
/ Interleukin 10
/ Iontophoresis
/ laser Doppler flowmetry
/ Lipids
/ Male
/ Microcirculation
/ microvascular
/ Microvasculature
/ n-3 polyunsaturated fatty acids
/ Nitric oxide
/ omega-3 polyunsaturated fatty acids
/ Polyunsaturated fatty acids
/ Skin - blood supply
/ Skin - drug effects
/ Sodium nitroprusside
/ Studies
/ Triglycerides
/ Vascular endothelial growth factor
/ Vasodilation
/ Vasodilation - drug effects
/ Vasodilation - physiology
/ Young Adult
/ γ-Interferon
2020
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Anti-Inflammatory Potential of n-3 Polyunsaturated Fatty Acids Enriched Hen Eggs Consumption in Improving Microvascular Endothelial Function of Healthy Individuals-Clinical Trial
by
Kolar, Luka
, Stupin, Marko
, Grčević, Manuela
, Šerić, Vatroslav
, Stupin, Ana
, Matić, Anita
, Mihalj, Martina
, Kolobarić, Nikolina
, Mihaljević, Zrinka
, Šušnjara, Petar
, Kralik, Zlata
, Jukić, Ivana
, Kralik, Gordana
, Drenjančević, Ines
in
Acetylcholine
/ Activation
/ Adult
/ Animals
/ Anti-inflammatory agents
/ Anti-Inflammatory Agents - analysis
/ Anti-Inflammatory Agents - chemistry
/ Anti-Inflammatory Agents - pharmacology
/ Anti-Inflammatory Agents, Non-Steroidal - chemistry
/ Anti-Inflammatory Agents, Non-Steroidal - pharmacology
/ Atherosclerosis
/ Blood Chemical Analysis
/ Blood flow
/ Blood pressure
/ Body composition
/ Body composition (biology)
/ Body Composition - drug effects
/ Body fat
/ Body fluids
/ Body water
/ Chickens
/ Cholesterol
/ Consumption
/ Cytokines - blood
/ Doppler effect
/ Eggs
/ Eggs - analysis
/ Endothelium
/ Endothelium, Vascular - drug effects
/ Endothelium, Vascular - physiology
/ Enrichment
/ Fatty acids
/ Fatty Acids - blood
/ Fatty Acids, Omega-3 - analysis
/ Fatty Acids, Omega-3 - chemistry
/ Fatty Acids, Omega-3 - pharmacology
/ Female
/ Food
/ Food, Fortified
/ Functional foods & nutraceuticals
/ Growth factors
/ Hemodynamics - drug effects
/ Humans
/ Inflammation
/ Interferon
/ Interleukin
/ Interleukin 10
/ Iontophoresis
/ laser Doppler flowmetry
/ Lipids
/ Male
/ Microcirculation
/ microvascular
/ Microvasculature
/ n-3 polyunsaturated fatty acids
/ Nitric oxide
/ omega-3 polyunsaturated fatty acids
/ Polyunsaturated fatty acids
/ Skin - blood supply
/ Skin - drug effects
/ Sodium nitroprusside
/ Studies
/ Triglycerides
/ Vascular endothelial growth factor
/ Vasodilation
/ Vasodilation - drug effects
/ Vasodilation - physiology
/ Young Adult
/ γ-Interferon
2020
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![Anti-Inflammatory Potential of n-3 Polyunsaturated Fatty Acids Enriched Hen Eggs Consumption in Improving Microvascular Endothelial Function of Healthy Individuals-Clinical Trial](https://www.mbrl.ae/o/mbrl-theme/images/site-assets/generic/no-book-image.png)
Anti-Inflammatory Potential of n-3 Polyunsaturated Fatty Acids Enriched Hen Eggs Consumption in Improving Microvascular Endothelial Function of Healthy Individuals-Clinical Trial
by
Kolar, Luka
, Stupin, Marko
, Grčević, Manuela
, Šerić, Vatroslav
, Stupin, Ana
, Matić, Anita
, Mihalj, Martina
, Kolobarić, Nikolina
, Mihaljević, Zrinka
, Šušnjara, Petar
, Kralik, Zlata
, Jukić, Ivana
, Kralik, Gordana
, Drenjančević, Ines
in
Acetylcholine
/ Activation
/ Adult
/ Animals
/ Anti-inflammatory agents
/ Anti-Inflammatory Agents - analysis
/ Anti-Inflammatory Agents - chemistry
/ Anti-Inflammatory Agents - pharmacology
/ Anti-Inflammatory Agents, Non-Steroidal - chemistry
/ Anti-Inflammatory Agents, Non-Steroidal - pharmacology
/ Atherosclerosis
/ Blood Chemical Analysis
/ Blood flow
/ Blood pressure
/ Body composition
/ Body composition (biology)
/ Body Composition - drug effects
/ Body fat
/ Body fluids
/ Body water
/ Chickens
/ Cholesterol
/ Consumption
/ Cytokines - blood
/ Doppler effect
/ Eggs
/ Eggs - analysis
/ Endothelium
/ Endothelium, Vascular - drug effects
/ Endothelium, Vascular - physiology
/ Enrichment
/ Fatty acids
/ Fatty Acids - blood
/ Fatty Acids, Omega-3 - analysis
/ Fatty Acids, Omega-3 - chemistry
/ Fatty Acids, Omega-3 - pharmacology
/ Female
/ Food
/ Food, Fortified
/ Functional foods & nutraceuticals
/ Growth factors
/ Hemodynamics - drug effects
/ Humans
/ Inflammation
/ Interferon
/ Interleukin
/ Interleukin 10
/ Iontophoresis
/ laser Doppler flowmetry
/ Lipids
/ Male
/ Microcirculation
/ microvascular
/ Microvasculature
/ n-3 polyunsaturated fatty acids
/ Nitric oxide
/ omega-3 polyunsaturated fatty acids
/ Polyunsaturated fatty acids
/ Skin - blood supply
/ Skin - drug effects
/ Sodium nitroprusside
/ Studies
/ Triglycerides
/ Vascular endothelial growth factor
/ Vasodilation
/ Vasodilation - drug effects
/ Vasodilation - physiology
/ Young Adult
/ γ-Interferon
2020
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Anti-Inflammatory Potential of n-3 Polyunsaturated Fatty Acids Enriched Hen Eggs Consumption in Improving Microvascular Endothelial Function of Healthy Individuals-Clinical Trial
![Anti-Inflammatory Potential of n-3 Polyunsaturated Fatty Acids Enriched Hen Eggs Consumption in Improving Microvascular Endothelial Function of Healthy Individuals-Clinical Trial](https://syndetics.com/index.aspx?isbn=/mc.gif&issn=1422-0067&client=MBRL&type=mbrl)
Journal Article
Anti-Inflammatory Potential of n-3 Polyunsaturated Fatty Acids Enriched Hen Eggs Consumption in Improving Microvascular Endothelial Function of Healthy Individuals-Clinical Trial
2020
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Overview
The effects of consumption of n-3 polyunsaturated fatty acids (n-3 PUFAs) enriched hen eggs on endothelium-dependent and endothelium-independent vasodilation in microcirculation, and on endothelial activation and inflammation were determined in young healthy individuals. Control group (
= 21) ate three regular hen eggs/daily (249 mg n-3 PUFAs/day), and n-3 PUFAs group (
= 19) ate three n-3 PUFAs enriched hen eggs/daily (1053 g n-3 PUFAs/day) for 3 weeks. Skin microvascular blood flow in response to iontophoresis of acetylcholine (AChID; endothelium-dependent) and sodium nitroprusside (SNPID; endothelium-independent) was assessed by laser Doppler flowmetry. Blood pressure (BP), body composition, body fluid status, serum lipid and free fatty acids profile, and inflammatory and endothelial activation markers were measured before and after respective dietary protocol. Results: Serum n-3 PUFAs concentration significantly increased, AChID significantly improved, and SNPID remained unchanged in n-3 PUFAs group, while none was changed in Control group. Interferon-γ (pro-inflammatory) significantly decreased and interleukin-10 (anti-inflammatory) significantly increased in n-3 PUFAs. BP, fat free mass, and total body water significantly decreased, while fat mass, interleukin-17A (pro-inflammatory), interleukin-10 and vascular endothelial growth factor A significantly increased in the Control group. Other measured parameters remained unchanged in both groups. Favorable anti-inflammatory properties of n-3 PUFAs consumption potentially contribute to the improvement of microvascular endothelium-dependent vasodilation in healthy individuals.
Publisher
MDPI AG,MDPI
Subject
/ Adult
/ Animals
/ Anti-Inflammatory Agents - analysis
/ Anti-Inflammatory Agents - chemistry
/ Anti-Inflammatory Agents - pharmacology
/ Anti-Inflammatory Agents, Non-Steroidal - chemistry
/ Anti-Inflammatory Agents, Non-Steroidal - pharmacology
/ Body Composition - drug effects
/ Body fat
/ Chickens
/ Eggs
/ Endothelium, Vascular - drug effects
/ Endothelium, Vascular - physiology
/ Fatty Acids, Omega-3 - analysis
/ Fatty Acids, Omega-3 - chemistry
/ Fatty Acids, Omega-3 - pharmacology
/ Female
/ Food
/ Functional foods & nutraceuticals
/ Humans
/ Lipids
/ Male
/ n-3 polyunsaturated fatty acids
/ omega-3 polyunsaturated fatty acids
/ Studies
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