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Histone lactylation links metabolism and gene regulation
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Histone lactylation links metabolism and gene regulation
Histone lactylation links metabolism and gene regulation
Journal Article

Histone lactylation links metabolism and gene regulation

2019
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Overview
Cells regulate gene expression in part through the chemical labelling of histone proteins. Discovery of a label derived from lactate molecules reveals a way in which cells link gene expression to nutrient metabolism. Lactylation is a newly discovered epigenetic modification.
Publisher
Nature Publishing Group UK,Nature Publishing Group