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Pexelizumab fails to inhibit assembly of the terminal complement complex in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention. Insight from a substudy of the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX-AMI) trial
by
Lin, Gen-Min
, Jaiteh, Lamin E.S.
, Li, Yi-Hwei
, Han, Chih-Lu
in
Angioplasty, Balloon, Coronary
/ Antibodies, Monoclonal, Humanized - therapeutic use
/ Cardiology
/ Cardiovascular
/ Cell culture
/ Complement Membrane Attack Complex - antagonists & inhibitors
/ Cytokines
/ Female
/ Heart attacks
/ Humans
/ Ischemia
/ Male
/ Myocardial Infarction - therapy
/ Single-Chain Antibodies - therapeutic use
2012
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Pexelizumab fails to inhibit assembly of the terminal complement complex in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention. Insight from a substudy of the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX-AMI) trial
by
Lin, Gen-Min
, Jaiteh, Lamin E.S.
, Li, Yi-Hwei
, Han, Chih-Lu
in
Angioplasty, Balloon, Coronary
/ Antibodies, Monoclonal, Humanized - therapeutic use
/ Cardiology
/ Cardiovascular
/ Cell culture
/ Complement Membrane Attack Complex - antagonists & inhibitors
/ Cytokines
/ Female
/ Heart attacks
/ Humans
/ Ischemia
/ Male
/ Myocardial Infarction - therapy
/ Single-Chain Antibodies - therapeutic use
2012
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Pexelizumab fails to inhibit assembly of the terminal complement complex in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention. Insight from a substudy of the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX-AMI) trial
by
Lin, Gen-Min
, Jaiteh, Lamin E.S.
, Li, Yi-Hwei
, Han, Chih-Lu
in
Angioplasty, Balloon, Coronary
/ Antibodies, Monoclonal, Humanized - therapeutic use
/ Cardiology
/ Cardiovascular
/ Cell culture
/ Complement Membrane Attack Complex - antagonists & inhibitors
/ Cytokines
/ Female
/ Heart attacks
/ Humans
/ Ischemia
/ Male
/ Myocardial Infarction - therapy
/ Single-Chain Antibodies - therapeutic use
2012
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Pexelizumab fails to inhibit assembly of the terminal complement complex in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention. Insight from a substudy of the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX-AMI) trial
Journal Article
Pexelizumab fails to inhibit assembly of the terminal complement complex in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention. Insight from a substudy of the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX-AMI) trial
2012
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Overview
[...]pexelizumab may reduce cell-bound C5b-9 amount in myocardium resulting in less cardiac ischemia/reperfusion injury than controls.
Publisher
Mosby, Inc,Elsevier Limited
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