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Body-Weight Fluctuations and Outcomes in Coronary Disease
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Journal Article
Body-Weight Fluctuations and Outcomes in Coronary Disease
2017
Overview
This secondary analysis of findings from a trial that assessed the effect of low-density lipoprotein cholesterol levels in patients with coronary artery disease shows that body-weight fluctuation was associated with an increased risk of death and cardiovascular events.
Obesity is an independent risk factor for cardiovascular death and disease.
1
,
2
Among participants in the Framingham Heart Study who were between 35 and 75 years of age and were followed for up to 44 years, overweight and obese participants were at a higher risk for the development of cardiovascular disease than participants of normal weight.
3
Weight gain is strongly associated with an increased risk of death and disease among participants without evident cardiovascular disease at baseline.
4
,
5
Indeed, in obese persons, bariatric surgery followed by weight loss reduces the risk of cardiovascular disease, including hypertension, hypercholesterolemia, and diabetes.
6
– . . .
Publisher
Massachusetts Medical Society
Subject
/ Angina
/ Anticholesteremic Agents - therapeutic use
/ Atorvastatin - therapeutic use
/ Cardiovascular Diseases - epidemiology
/ Coronary Artery Disease - blood
/ Coronary Artery Disease - drug therapy
/ Coronary Artery Disease - mortality
/ Coronary Artery Disease - physiopathology
/ Death
/ Diabetes
/ Female
/ Humans
/ Male
/ Patients
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