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Effect of Exercise on the Cognitive Function of Older Patients With Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis
by
Wang, Zi
, Cai, Yi-Hui
, Ni, Guo-Xin
, Feng, Le-Yi
in
Aging
/ Bias
/ Clinical trials
/ Cognition & reasoning
/ Cognitive ability
/ Dementia disorders
/ Diabetes
/ Diabetes mellitus (non-insulin dependent)
/ Exercise
/ Intervention
/ Meta-analysis
/ Older people
/ Physical fitness
/ Risk factors
/ Software
2022
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Effect of Exercise on the Cognitive Function of Older Patients With Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis
by
Wang, Zi
, Cai, Yi-Hui
, Ni, Guo-Xin
, Feng, Le-Yi
in
Aging
/ Bias
/ Clinical trials
/ Cognition & reasoning
/ Cognitive ability
/ Dementia disorders
/ Diabetes
/ Diabetes mellitus (non-insulin dependent)
/ Exercise
/ Intervention
/ Meta-analysis
/ Older people
/ Physical fitness
/ Risk factors
/ Software
2022
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Do you wish to request the book?
Effect of Exercise on the Cognitive Function of Older Patients With Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis
by
Wang, Zi
, Cai, Yi-Hui
, Ni, Guo-Xin
, Feng, Le-Yi
in
Aging
/ Bias
/ Clinical trials
/ Cognition & reasoning
/ Cognitive ability
/ Dementia disorders
/ Diabetes
/ Diabetes mellitus (non-insulin dependent)
/ Exercise
/ Intervention
/ Meta-analysis
/ Older people
/ Physical fitness
/ Risk factors
/ Software
2022
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Effect of Exercise on the Cognitive Function of Older Patients With Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis
Journal Article
Effect of Exercise on the Cognitive Function of Older Patients With Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis
2022
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Overview
Background: Ageing and type 2 diabetes mellitus (T2DM) are important risk factors for the development of cognitive deterioration and dementia. The objective of this research was to investigate the effects of an exercise intervention on cognitive function in older T2DM patients. Methods: Eight literature databases (PubMed, EBSCO, Scopus, Embase, The Cochrane Library, Web of Science, Ovid, and ProQuest) were searched from inception to January 20, 2022. The researchers examined Randomized controlled trials (RCTs) that evaluated the impact of exercise on the cognitive performance of older T2DM patients. The Cochrane risk-of-bias tool (ROB 2) for RCTs was used to assess each study. The quality of evidence was assessed using the GRADE (Grading of Recommendations, Assessment, Development, and Evaluations) approach. The Mini-Mental State Examination (MMSE), Modified MMSE (3MSE), and Montreal Cognitive Assessment (MoCA) were used to evaluate the cognitive outcomes. We performed a subgroup analysis with stratification according to exercise intervention modality, duration, and cognitive impairment. Results: Five trials were eligible, with a total of 738 T2DM patients. The combined findings revealed that exercise improved global cognitive function significantly (standardized mean difference: 1.34, 95% confidence interval: 0.23 – 2.44, p 0.05). In the studies that were included, no relevant adverse events were reported. Conclusions: Exercise is beneficial in improving global cognitive function in older adults with T2DM. Studies with bigger sample sizes and higher quality are additionally expected to draw more definite conclusions.
Publisher
Frontiers Research Foundation
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