Asset Details
Do you wish to reserve the book?
Pulmonary-Resident Memory Lymphocytes: Pivotal Orchestrators of Local Immunity Against Respiratory Infections
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Pulmonary-Resident Memory Lymphocytes: Pivotal Orchestrators of Local Immunity Against Respiratory Infections
Do you wish to request the book?
Pulmonary-Resident Memory Lymphocytes: Pivotal Orchestrators of Local Immunity Against Respiratory Infections
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Pulmonary-Resident Memory Lymphocytes: Pivotal Orchestrators of Local Immunity Against Respiratory Infections
2021
Overview
There is increasing evidence that lung-resident memory T and B cells play a critical role in protecting against respiratory reinfection. With a unique transcriptional and phenotypic profile, resident memory lymphocytes are maintained in a quiescent state, constantly surveying the lung for microbial intruders. Upon reactivation with cognate antigen, these cells provide rapid effector function to enhance immunity and prevent infection. Immunization strategies designed to induce their formation, alongside novel techniques enabling their detection, have the potential to accelerate and transform vaccine development. Despite most data originating from murine studies, this review will discuss recent insights into the generation, maintenance and characterisation of pulmonary resident memory lymphocytes in the context of respiratory infection and vaccination using recent findings from human and non-human primate studies.
Publisher
Frontiers Media SA,Frontiers Media S.A
Subject
/ Antigens
/ Bacterial Infections - immunology
/ Bacterial Infections - metabolism
/ Bacterial Infections - microbiology
/ Bacterial Infections - prevention & control
/ Bacterial Vaccines - administration & dosage
/ Bacterial Vaccines - immunology
/ Humans
/ Immunity
/ Ligands
/ lung
/ Lungs
/ Memory B Cells - microbiology
/ Memory T Cells - microbiology
/ Plasma
/ Respiratory Tract Infections - immunology
/ Respiratory Tract Infections - microbiology
/ Respiratory Tract Infections - prevention & control
/ Respiratory Tract Infections - virology
/ Viral Vaccines - administration & dosage
