Asset Details
Do you wish to reserve the book?
Evaluation of variations in urine laminin-γ2 monomer in non-muscle-invasive bladder cancer before and after transurethral resection of the bladder tumor
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Evaluation of variations in urine laminin-γ2 monomer in non-muscle-invasive bladder cancer before and after transurethral resection of the bladder tumor
Do you wish to request the book?
Evaluation of variations in urine laminin-γ2 monomer in non-muscle-invasive bladder cancer before and after transurethral resection of the bladder tumor
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Evaluation of variations in urine laminin-γ2 monomer in non-muscle-invasive bladder cancer before and after transurethral resection of the bladder tumor
2026
Overview
Background
We have previously reported urine laminin-γ2 monomer (Lm-γ2m) as a diagnostic biomarker for patients with non-muscle-invasive bladder cancer (NMIBC). However, Lm-γ2m has not been evaluated as a prognostic biomarker for patients with NMIBC after transurethral resection of bladder tumor (TURBT). This study aimed to clarify whether urine Lm-γ2m offers a useful prognostic biomarker for patients with NMIBC after TURBT.
Methods
Participants comprised 41 patients with NMIBC. Urine Lm-γ2m was prospectively measured before and 3 months after TURBT and values were compared. Traditional urine tumor markers such as urine nuclear matrix protein 22 and cytology were also evaluated before and after TURBT. Patients were stratified by the presence of recurrence within 1 year after TURBT and values of urine Lm-γ2m before and after TURBT were analyzed.
Results
Mean urine Lm-γ2m values were significantly decreased after TURBT compared to before surgery. Mean urine Lm-γ2m before and after TURBT were higher in patients with recurrence within 1 year after surgery than in patients without recurrence. Urine Lm-γ2m before TURBT was also important to predict prognosis in patients with NMIBC treated using TURBT.
Conclusions
These results suggest urine Lm-γ2m as a potentially useful biomarker for NMIBC before and after TURBT.
Publisher
BioMed Central,Springer Nature B.V,BMC
Subject
/ Biomedical and Life Sciences
/ Cytology
/ Female
/ Health Promotion and Disease Prevention
/ Humans
/ Invasive bladder cancer, laminin
/ Laminin
/ Male
/ Monomers
/ Muscle
/ Neoplasm Recurrence, Local - urine
/ Non-Muscle Invasive Bladder Neoplasms - pathology
/ Non-Muscle Invasive Bladder Neoplasms - surgery
/ Non-Muscle Invasive Bladder Neoplasms - urine
/ Oncology
/ Patients
/ Surgery
/ Transurethral Resection of Bladder
/ Tumors
/ Urinary Bladder Neoplasms - pathology
/ Urinary Bladder Neoplasms - surgery
/ Urinary Bladder Neoplasms - urine
/ Urine
/ Urology
