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Serositis as possible manifestation in MDS/AML patients with complex karyotype and TP53 mutation: case series
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Serositis as possible manifestation in MDS/AML patients with complex karyotype and TP53 mutation: case series
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Journal Article
Serositis as possible manifestation in MDS/AML patients with complex karyotype and TP53 mutation: case series
2026
Overview
Myelodysplastic syndromes (MDS) and Acute Myeloid Leukemia (AML) are increasingly recognized to exhibit immune dysregulation, which can occasionally present with autoinflammatory manifestations. We describe four patients with MDS/AML harboring p53 mutations and a complex karyotype who developed inflammatory serositis without infectious correlation. All patients showed clinical improvement following corticosteroid therapy.
Publisher
Springer Berlin Heidelberg,Springer Nature B.V,Springer
Subject
/ Aged
/ Disease
/ Dyspnea
/ Female
/ Fever
/ Humans
/ Kidneys
/ Lavage
/ Leukemia
/ Leukemia, Myeloid, Acute - complications
/ Leukemia, Myeloid, Acute - diagnosis
/ Leukemia, Myeloid, Acute - drug therapy
/ Leukemia, Myeloid, Acute - genetics
/ Male
/ MDS/AML
/ Medicine
/ Mutation
/ Myelodysplastic Syndromes - complications
/ Myelodysplastic Syndromes - diagnosis
/ Myelodysplastic Syndromes - drug therapy
/ Myelodysplastic Syndromes - genetics
/ Oncology
/ Ostomy
/ Patients
/ Steroids
/ Tumor Suppressor Protein p53 - genetics
/ Urine
/ X-rays
