Asset Details
Do you wish to reserve the book?
In-vitro anti-inflammatory and antagonistic efficacy of polymyxin B capped silver nanoparticles in multi drug resistant Acinetobacter baumannii
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
In-vitro anti-inflammatory and antagonistic efficacy of polymyxin B capped silver nanoparticles in multi drug resistant Acinetobacter baumannii
Do you wish to request the book?
In-vitro anti-inflammatory and antagonistic efficacy of polymyxin B capped silver nanoparticles in multi drug resistant Acinetobacter baumannii
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
In-vitro anti-inflammatory and antagonistic efficacy of polymyxin B capped silver nanoparticles in multi drug resistant Acinetobacter baumannii
2025
Overview
Multidrug resistant
Acinetobacter baumannii
is declared as crucial level precedence pathogen by World Health Organization that needs new and upgraded antibiotics for better treatment. Against a vast extent of microbes, many silver nanoparticles have displayed anti-microbial activity because of their numerous methods of antimicrobial actions. This study was aimed to isolate and characterize the
Acinetobacter baumannii
by using standard microbiological technique and to analyze the anti-inflammatory and antagonistic effect of PB capped AgNPs in isolated
A
.
baumannii
. In antagonistic activity, PB capped AgNPs showed antagonistic effect in 8 out of 20 isolates tested and PB when combined with AgNPs showed antagonistic effect in all isolates tested. In in-vitro anti-inflammatory egg albumin assay, PB capped AgNPs gave inhibition rate of 96% at 12.5 µg, 93% at 25 µg, 82% at 50 µg and 62% at 100 µg whereas in Polymyxin B combined AgNPs it gave inhibition rate of 97% at the dose of 50 µg. In-silico analysis also showed that PB in combination with tri-sodium citrate gave good binding energy than tri-sodium citrate and Polymyxin used alone. Hence, this study represented that silver nanoparticles when used in combination proved to be a good alternative in the treatment of MDR
Acinetobacter baumannii
.
Publisher
Nature Publishing Group UK,Nature Publishing Group,Nature Portfolio
Subject
/ 631/61
/ Acinetobacter baumannii - drug effects
/ Acinetobacter baumannii - isolation & purification
/ Acinetobacter Infections - drug therapy
/ Acinetobacter Infections - microbiology
/ AgNPs
/ Anti-Bacterial Agents - chemistry
/ Anti-Bacterial Agents - pharmacology
/ Anti-Inflammatory Agents - chemistry
/ Anti-Inflammatory Agents - pharmacology
/ Drug Resistance, Multiple, Bacterial - drug effects
/ Humanities and Social Sciences
/ Humans
/ Metal Nanoparticles - chemistry
/ Science
/ Silver
