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Hypothermic Machine Perfusion in Liver Transplantation — A Randomized Trial

by Darwish Murad, Sarwa , Gilbo, Nicholas , Heaton, Nigel , Slangen, Jules J.G , Polak, Wojciech G , Vanlander, Aude , van Rijn, Rianne , de Meijer, Vincent E , van den Berg, Aad P , Porte, Robert J , Erdmann, Joris I , Jochmans, Ina , de Haas, Robbert J , van Leeuwen, Otto B , de Vries, Yvonne , van Hoek, Bart , Huurman, Volkert A.L , Cortes Cerisuelo, Miriam , Troisi, Roberto I , Schurink, Ivo J , Monbaliu, Diethard , de Jonge, Jeroen

in Adult / Adverse events / Allografts / Biliary Tract - pathology / Chirurgie / Cold Ischemia / Cold Temperature / Constriction, Pathologic - prevention & control / Cryopreservation / Death / Donors / Female / Human health sciences / Humans / Ischemia / Liver / Liver Transplantation / Liver transplants / Male / Medical equipment / Middle Aged / Organ Preservation - methods / Patients / Perfusion / Reperfusion Injury - prevention & control / Sciences de la santé humaine / Stricture / Surgery / Veins & arteries

2021

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Hypothermic Machine Perfusion in Liver Transplantation — A Randomized Trial

2021

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Hypothermic Machine Perfusion in Liver Transplantation — A Randomized Trial

2021

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Journal Article

Hypothermic Machine Perfusion in Liver Transplantation — A Randomized Trial

Darwish Murad, Sarwa,

Gilbo, Nicholas,

Heaton, Nigel,

Slangen, Jules J.G,

Polak, Wojciech G,

Vanlander, Aude,

van Rijn, Rianne,

de Meijer, Vincent E,

van den Berg, Aad P,

Porte, Robert J,

Erdmann, Joris I,

Jochmans, Ina,

de Haas, Robbert J,

van Leeuwen, Otto B,

de Vries, Yvonne,

van Hoek, Bart,

Huurman, Volkert A.L,

Cortes Cerisuelo, Miriam,

Troisi, Roberto I,

Schurink, Ivo J,

Monbaliu, Diethard,

de Jonge, Jeroen

2021

Overview

In a multicenter, controlled trial, patients undergoing transplantation of a liver from a donor after circulatory death were randomly assigned to receive the liver after hypothermic oxygenated machine perfusion or conventional static cold storage. Hypothermic perfusion led to a lower risk of post-transplantation nonanastomotic biliary strictures.

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Publisher

Massachusetts Medical Society,Massachussetts Medical Society

Subject

Adult

/ Adverse events

/ Allografts

/ Biliary Tract - pathology

/ Chirurgie

/ Cold Ischemia

/ Cold Temperature