Asset Details
Do you wish to reserve the book?
Platelet lysate gel and endothelial progenitors stimulate microvascular network formation in vitro: tissue engineering implications
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Platelet lysate gel and endothelial progenitors stimulate microvascular network formation in vitro: tissue engineering implications
Do you wish to request the book?
Platelet lysate gel and endothelial progenitors stimulate microvascular network formation in vitro: tissue engineering implications
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Platelet lysate gel and endothelial progenitors stimulate microvascular network formation in vitro: tissue engineering implications
2016
Overview
Revascularisation is a key step for tissue regeneration and complete organ engineering. We describe the generation of human platelet lysate gel (hPLG), an extracellular matrix preparation from human platelets able to support the proliferation of endothelial colony forming cells (ECFCs) in 2D cultures and the formation of a complete microvascular network
in vitro
in 3D cultures. Existing extracellular matrix preparations require addition of high concentrations of recombinant growth factors and allow only limited formation of capillary-like structures. Additional advantages of our approach over existing extracellular matrices are the absence of any animal product in the composition hPLG and the possibility of obtaining hPLG from patients to generate homologous scaffolds for re-implantation. This discovery has the potential to accelerate the development of regenerative medicine applications based on implantation of microvascular networks expanded
ex vivo
or the generation of fully vascularised organs.
Publisher
Nature Publishing Group UK,Nature Publishing Group
