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Sensitization of Candida albicans to terbinafine by berberine and berberrubine
by
LAM, KIM HUNG
, BIAN, ZHAOXIANG
, LEE, KENNETH KA HO
, WONG, WAI YEUNG
, LAM, PIKLING
, HAU, DESMOND KWOK PO
, KOK, STANTON HON LUNG
, CHUI, CHUNG HIN
, GAMBARI, ROBERTO
in
Alkaloids
/ antifungal
/ Berberine
/ berberrubine
/ C. albicans
/ Cancer therapies
/ Candida albicans
/ Candidiasis
/ Causes of
/ Complications and side effects
/ Dosage
/ Dosage and administration
/ Drug therapy
/ Drugs
/ Fourier transforms
/ Fungi
/ Fungicides
/ Herbal medicine
/ HIV
/ Human immunodeficiency virus
/ Immunocompromised hosts
/ Medicinal plants
/ Mycoses
/ NMR
/ Nuclear magnetic resonance
/ Opportunist infection
/ Physiological aspects
/ Pyrolysis
/ Terbinafine
/ Traditional Chinese medicine
2016
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Sensitization of Candida albicans to terbinafine by berberine and berberrubine
by
LAM, KIM HUNG
, BIAN, ZHAOXIANG
, LEE, KENNETH KA HO
, WONG, WAI YEUNG
, LAM, PIKLING
, HAU, DESMOND KWOK PO
, KOK, STANTON HON LUNG
, CHUI, CHUNG HIN
, GAMBARI, ROBERTO
in
Alkaloids
/ antifungal
/ Berberine
/ berberrubine
/ C. albicans
/ Cancer therapies
/ Candida albicans
/ Candidiasis
/ Causes of
/ Complications and side effects
/ Dosage
/ Dosage and administration
/ Drug therapy
/ Drugs
/ Fourier transforms
/ Fungi
/ Fungicides
/ Herbal medicine
/ HIV
/ Human immunodeficiency virus
/ Immunocompromised hosts
/ Medicinal plants
/ Mycoses
/ NMR
/ Nuclear magnetic resonance
/ Opportunist infection
/ Physiological aspects
/ Pyrolysis
/ Terbinafine
/ Traditional Chinese medicine
2016
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Sensitization of Candida albicans to terbinafine by berberine and berberrubine
by
LAM, KIM HUNG
, BIAN, ZHAOXIANG
, LEE, KENNETH KA HO
, WONG, WAI YEUNG
, LAM, PIKLING
, HAU, DESMOND KWOK PO
, KOK, STANTON HON LUNG
, CHUI, CHUNG HIN
, GAMBARI, ROBERTO
in
Alkaloids
/ antifungal
/ Berberine
/ berberrubine
/ C. albicans
/ Cancer therapies
/ Candida albicans
/ Candidiasis
/ Causes of
/ Complications and side effects
/ Dosage
/ Dosage and administration
/ Drug therapy
/ Drugs
/ Fourier transforms
/ Fungi
/ Fungicides
/ Herbal medicine
/ HIV
/ Human immunodeficiency virus
/ Immunocompromised hosts
/ Medicinal plants
/ Mycoses
/ NMR
/ Nuclear magnetic resonance
/ Opportunist infection
/ Physiological aspects
/ Pyrolysis
/ Terbinafine
/ Traditional Chinese medicine
2016
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Sensitization of Candida albicans to terbinafine by berberine and berberrubine
Journal Article
Sensitization of Candida albicans to terbinafine by berberine and berberrubine
2016
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Overview
Candida albicans (C. albicans) is an opportunistic fungal pathogen, particularly observed in immunocompromised patients. C. albicans accounts for 50-70% of cases of invasive candidiasis in the majority of clinical settings. Terbinafine, an allylamine antifungal drug, has been used to treat fungal infections previously. It has fungistatic activity against C. albicans. Traditional Chinese medicines can be used as complementary medicines to conventional drugs to treat a variety of ailments and diseases. Berberine is a quaternary alkaloid isolated from the traditional Chinese herb, Coptidis Rhizoma, while berberrubine is isolated from the medicinal plant Berberis vulgaris, but is also readily derived from berberine by pyrolysis. The present study demonstrates the possible complementary use of berberine and berberrubine with terbinafine against C. albicans. The experimental findings assume that the potential application of these alkaloids together with reduced dosage of the standard drug would enhance the resulting antifungal potency.
Publisher
D.A. Spandidos,Spandidos Publications,Spandidos Publications UK Ltd
Subject
/ Complications and side effects
/ Dosage
/ Drugs
/ Fungi
/ HIV
/ Human immunodeficiency virus
/ Mycoses
/ NMR
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